Cytokine bioassays

Combinations of cytokine reporter cell lines, bioactive cytokines, and neutralizing antibodies

InvivoGen's cytokine reporter cells are valuable tools for lead optimization and release assays of activator or inhibitor molecules. To improve the performance of these bioassays, we also provide recombinant bioactive cytokines and neutralizing monoclonal antibodies for each cell line that can serve as benchmarks. We guarantee the reproducible activity of these products through stringent quality control and extensive validation tests: each new lot is functionally tested using the combination of the other two matching products.

Cytokine offer: For each cytokine reporter cell line purchased, get a free vial of the matching cytokine.

Cytokine reporter cell lines - Sensitive monitoring of cytokine signaling

• Colorimetric cellular assays: featuring a SEAP reporter of NF-κB or STAT activation
• Convenient readout using QUANTI-Blue™, a SEAP detection reagent
• Reliable and consistent performance
• Stability guaranteed for 20 passages

Recombinant cytokines - Potent signaling inducers

• Highly competitive pricing for Interleukins, Interferons, Growth Factors, Tumor Necrosis Factors
• Guaranteed bioactivity
• High purity: > 95%
• Verified absence of endotoxins

Cytokine & Cytokine receptor antibodies - Specific blocking of cytokine signaling

• Monoclonal antibodies targeting cytokines or cytokine receptors
• Derived from well-referenced biosimilars or in-house hybridoma
• Guaranteed neutralization 
• Verified absence of endotoxins