Collection of monoclonal antibodies targeting different Toll-like receptors
InvivoGen provides a collection of monoclonal antibodies (mAbs) targeting human or murine Toll-Like receptors (TLRs).
TLRs are the most famous family of pattern recognition receptors (PRRs) identified in mammals. They initiate key inflammatory responses and also shape adaptative immunity. TLRs recognize diverse pathogen-associated molecular patterns (PAMPs) from bacteria, fungi, parasites, and viruses. Moreover, they are implicated in several inflammatory and immune disorders and play a role in cancer and vaccine research.
The provided antibodies target human or murine TLR1, TLR2, TLR4, TLR5, or TLR6. They are either produced in hybridoma or Chinese hamster ovary (CHO) cells using recombinant technology and purified by affinity chromatography. They can be used for various applications including neutralization, Western blot, immunoprecipitation, immunohistochemistry (IC), or flow cytometry.
Key features
- Targets the human or murine Toll-like receptors
- Each lot is functionally tested
- Guaranteed free of bacterial contaminants
Application
- Neutralization assay
- Detection (flow cytometry, IC, Western blot, etc.)
