InvivoGen offers an extensive panel of human cell lines designed to monitor TLR activity using inducible SEAP (secreted embryonic alkaline phosphatase) and/or Lucia Luciferase reporter systems. These cell lines are derived from HEK293 embryonic kidney or THP-1 monocytic cells.
Three types of TLR reporter cells are available:
— Endogenous TLR expression: cell lines that naturally express several TLR genes.
— TLR overexpression (OE): cell lines that have been transfected to stably express a human or murine TLR gene.
— TLR knockout (KO): cell lines that have been knocked out for the expression of a TLR gene.
InvivoGen also offers a selection of mouse TLR reporter cells derived from the RAW-264.7 macrophage cell line.
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TLR cell lines
