Toll-like receptor 2 (TLR2) is required for the recognition of a wide range of microbial molecules from Gram-positive and Gram-negative bacteria, as well as mycoplasma and yeast.
Specifically, TLR2 is involved in the recognition of cell-wall components, such as lipoproteins from Gram-negative and Gram-positive bacteria, lipoteichoic acid from Gram-positive bacteria only, lipoarabinomannan from mycobacteria, and zymosan from yeast.
TLR2 recognizes a wide range of ligands in association with TLR1 or TLR6.
InvivoGen provides a diverse collection of TLR2 ligands, which includes heat-killed bacteria and several cell-wall components.
These TLR2 ligands are biologically validated using HEK-Blue™ TLR2 Cells.