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Cell Lines

InvivoGen offers a large panel of human and mouse cell lines

These cell lines are designed to:

  • Study specific gene function(s)
  • Investigate cell signaling pathways and signal transduction
  • Screen for agonists/antagonists of pattern recognition receptors (PRRs), such as Toll-like receptors (TLRs), C-type lectin receptors (CLRs), cytosolic DNA sensors (CDSs), and aryl hydrocarbon receptor (AhR)
  • Control the expression of cytotoxic genes
  • Screen for toxic protein inhibitors
  • Measure cytokine production
  • Validate antibody functions

 

Various cell types

InvivoGen offers immortalized cell lines, isolated from various human or mouse tissues, that are widely used for in vitro biomedical research:

  Human cell lines

  Mouse cell lines

Expanding collection of reporter cell lines 

Most of our cell lines express an NF-κB-inducible SEAP (secreted embryonic alkaline phosphatase) and/or IRF-inducible Lucia luciferase. Both reporter proteins are secreted and thus can be readily detected in the cell supernatant using the appropriate detection reagent

Seven major families of reporter cells are available to meet your research needs:

  • Transcription factor reporter cells (NF-κB, IRF, or NFAT pathways)
  • PRR reporter cells (TLRs, CLRs, CDSs & STING, NLRs, RLRs, AhR, ALPK1/TIFA, inflammasomes)
  • Cytokine reporter cells
  • ADCC and ADCC cellular assays
  • Immune checkpoint cellular assays
  • Autophagy reporter cells
  • COVID-19 reporter cells

 

InvivoGen’s cell lines are extensively tested for viability, stability, biological activity, and absence of mycoplasma to ensure strong and reproducible results. Moreover, we provide detailed handling and experimental procedures for all cell lines, to minimize the need for optimization or troubleshooting by the end-user.

 

Upload our product flyer Download our product flyer presenting InvivoGen’s Reporter Cell Lines.

Visit our FAQ ANY QUESTIONS ABOUT OUR CELL LINES? VISIT OUR FREQUENTLY ASKED QUESTIONS PAGE

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