InvivoGen’s Reviews

Find all of our reviews below
Innate immunity / PRR
CLR types
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Review on C-Type Lectin Receptors

C-type lectin receptors (CLRs) comprise a large family of receptors that bind to carbohydrates in a...

Inflammasome / Innate immunity
Inflammasomes pathway
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Review on Inflammasomes

The nucleotide-binding oligomerization domain-like receptor (NLR) family of proteins is involved in...

Innate immunity / PRR
NLR subfamilies
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Review on Nod-Like Receptors

The cytosolic NOD-Like Receptors (NLRs, also known as CATERPILLERs, NODs or NALP/PAN/PYPAFs) are...

Innate immunity / PRR
TLR signaling pathways
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Review on Toll-Like Receptors

Toll-Like Receptors (TLRs) play a critical role in the early innate immune response to invading...

Vaccination
Mechanims of adjuvant in vaccines
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Review on vaccine Adjuvants

Adjuvants are essential for enhancing and directing the adaptative immune response to vaccine...

Products
RNAi-mediated gene silencing in  mammals using shRNAs
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RNA Interference

RNA interference (RNAi) is one of the most exciting discoveries of the past decade in functional...

Products
DNA-induced immune response
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CpG-free DNA Review

Review of the effect of  CpG dinucleotide on the immune response and the gene silencing of gene...

Innate immunity
TLR3 Pathway
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TLR3: racing for vaccine advantages

Toll-like receptors (TLRs) play a pivotal role in the initiation of prompt innate immune defenses...

Innate immunity / PRR
RIG-I-Like Receptors (RLR) and Cytosolic DNA Sensors (CDS) pathways
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RIG-I-Like Receptors & Cytosolic DNA Sensors

RIG-I-like receptors (RLRs) constitute a family of cytoplasmic RNA helicases that are critical for...

Innate immunity / PRR
innate immune signaling pathways activated by PamadiFectin™ (CL553)
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Multi-TLR Agonists: Potential for Therapeutic Success

Toll-like receptors (TLRs) are the best studied pattern recognition receptors (PRRs) and their...

Innate immunity / PRR / STING
cGAS pathway
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cGAS - The long awaited cytosolic DNA sensor?

Cytosolic DNA is well-known to induce the production of type I interferons (IFNs) through the STING...

COVID-19
Spotlight on COVID-19: Vaccine development
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Spotlight on COVID-19: Vaccine development

The global vaccine effort in response to the COVID-19 pandemic is unprecedented in terms of both...

Innate immunity / Inflammasome
Inflammasome-induced pyroptotic cell death
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Overview of Regulated Cell Death

Regulated cell death (RCD) is a lethal process taking place in the context of stressful stimuli (e.g...

COVID-19
Can immunity end the SARS-CoV-2 pandemic?
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Spotlight on COVID-19: Protective immunity & Re-infection

Learn more about the growing evidence that re-infection by SARS-CoV-2 can occur, with protective...

COVID-19
Spotlight on COVID-19: Predicated immune responses
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Spotlight on COVID-19: Predicted immune responses

Currently, there is very limited knowledge of the host immune response to SARS-CoV-2. However, based...

COVID-19
Spotlight on COVID-19: Treatment with repurposed drugs
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Spotlight on COVID-19: Treatment with repurposed drugs

Currently, there are no specific therapies approved for the treatment of coronavirus disease 2019...

COVID-19
The infection cycle of SARS-CoV-2
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Spotlight on COVID-19: Infection

COVID-19 is a pandemic that threatens global health. Its causative agent, SARS-CoV-2, a novel β...

Innate immunity
TLR7-TLR8 Pathway
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TLR7 & TLR8: fraternal twins

Toll-like receptors (TLRs) play a pivotal role in the initiation of anti-infectious immune responses...