Immunotherapy aims at modulating the immune system to fight against diseases. Biological tools can be used to either strengthen natural immunity in the context of infectious diseases and cancers or dampen immune responses in the context of auto-immune diseases/inflammatory conditions.
Examples of immunotherapies against cancer
Increasing knowledge on immune regulation mechanisms and technical advancements have allowed moving from broad to more precise therapeutic strategies.
InvivoGen is offering a large panel of immunotherapy-related products (reporter cell lines, clinically-relevant monoclonal antibodies, PRR ligands, and fusion proteins) to help investigate:
Immune Checkpoints (ICs): Co-inhibitory or co-stimulatory molecules expressed at the surface of immune cells that act as gatekeepers of immune responses.
Immune Stimulating Antibody Conjugates (ISACs): Engineered recombinant antibodies coupled to synthetic PRR ligands that potentiate immune responses by triggering the production of pro-inflammatory cytokines and chemokines.
- Vaccination: Formulation of specific antigens and adjuvants that induce adaptive protecting immune responses against pathogens causing diseases (prophylactic vaccines) or against established tumors (therapeutic vaccines).
InvivoGen's products are for research use only.