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Generating human macrophage and dentritic cell models from primary monocytes and THP-1 cells
Monocyte differentiation and polarization are widely used to generate macrophage and dendritic cell (DC) models for studying innate immune responses. However, experimental workflows can vary considerably depending on the cell model and differentiation or polarization conditions. In this application note, we demonstrate how InvivoGen’s M1 and M2 Polarization Mixes and DC Differentiation Mix provide standardized workflows adapted to human peripheral blood CD14+ monocytes and THP-1 cells.
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