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A Blue Shift in LDH release quantification
Cell death quantification is central to a broad range of in vitro applications, including immune effector function studies and drug-induced cytotoxicity. Lactate dehydrogenase (LDH) release assays are widely used to measure loss of membrane integrity and provide a simple and scalable approach for assessing cytotoxicity across diverse experimental settings. This review examines the principles and limitations of LDH-based assays, and how refining the colorimetric readout improves measurement reliability.
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