Raji-derived Target Cells
Human immune checkpoint target cells
Raji lymphoblast-like cells were established from a Burkitt lymphoma patient. Historically, these cells have been successfully used as target cells in human effector studies such as antibody-dependent cellular cytotoxicity (ADCC), either with peripheral blood mononuclear cells, Natural Killer cells, or Jurkat-derived reporter T cells.
InvivoGen offers an expanding collection of Raji-derived target cells that stably express a protein of interest for cancer therapeutic studies (e.g. immune checkpoints).