A secreted coelenterazine-utilizing luciferase
InvivoGen’s Lucia® luciferase is a completely novel and optimized luciferase with strong bioluminescent activity. It is expressed by a synthetic gene designed on natural secreted luciferase genes from marine copepods.
Lucia® luciferase generates 1000-fold higher bioluminescent signal compared to the commonly used Firefly and Renilla luciferases. Lucia® luciferase is designed for high and prolonged expression in mammalian cells.
Read our review on Luciferase and Lucia® luciferase
Lucia® luciferase has several advantages over currently available luciferases and reporter systems:
- Lucia® luciferase is efficiently secreted into the cell culture supernatant.
- Reporter activity is determined fast and easily in real-time without disturbing cells in one simple endpoint assay.
- Stable expression of Lucia luciferase makes this reporter system ideal for use in cell based assays and high-throughput applications.
The Lucia® luciferase reporter system provides an improvement in the sensitivity, reliability and ease of your live-cell reporter gene assays.
Note: Lucia® is a trademark of InvivoGen registered with the United States Patent and Trademark Office.