Luciferase Reporter System

A secreted coelenterazine-utilizing luciferase

InvivoGen’s Lucia luciferase is a completely novel and optimized luciferase with strong bioluminescent activity. It is expressed by a synthetic gene designed on natural secreted luciferase genes from marine copepods.

Lucia luciferase generates 1000-fold higher bioluminescent signal compared to the commonly used Firefly and Renilla luciferases. Lucia luciferase is designed for high and prolonged expression in mammalian cells.

Read our review on Luciferase and Lucia luciferase

Lucia luciferase has several advantages over currently available luciferases and reporter systems:

  • Lucia luciferase is efficiently secreted into the cell culture supernatant.
  • Reporter activity is determined fast and easily in real-time without disturbing cells in one simple endpoint assay.
  • Stable expression of Lucia luciferase makes this reporter system ideal for use in cell based assays and high-throughput applications.

The Lucia luciferase reporter system provides an improvement in the sensitivity, reliability and ease of your live-cell reporter gene assays.

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