Kinases are key enzymes involved in signal transduction. Specifically, these enzymes (also known as phosphotransferases) mediate the transfer of phosphate groups from high-energy molecules (such as ATP) to their substrate molecule.
This process of phosphorylation is critical for many different cellular functions, such as metabolism, angiogenesis, cell proliferation, and survival.
For your research needs, InvivoGen provides a large panel of high-quality kinase inhibitors that block the action of one or more protein kinases.
This family includes regulators of apical kinases, such as JAK1/JAK2, as well as inhibitors of downstream kinases, such as TBK1/IKKε, PI3K, IκB-α, MAPK, and MEK1/MEK2.