InvivoGen offers a selection of inhibitors targeting different innate immunity pathways.
Innate mmune pathway inhibitors are invaluable tools for both fundamental and translational research as they allow better understanding and precise modulation of complex inflammatory networks. They selectively block receptors/sensors (cGAS, STING), adaptors (MyD88, TRIF), signal transducers (TBK1, JAKs) or transcription factors (NF-kB, IRFs).
Applications
- Validation of mechanisms of action
- Study of signaling crosstalk
- Reduction of background & artifacts
- Disease modeling for therapeutic testing
Key features
- High purity (≥97%)
- Functionally validated using relevant cell-based assay
- Absence of bacterial contamination
See our Poster on Inhibitor Signaling Pathways
