TLR and Related Genes
Toll-Like Receptors interact with co-receptor molecules to recognize specific molecular patterns associated with microbial pathogens. Upon recognition, they induce distinct cellular responses that involve different adaptor proteins which in turn will activate a cascade of signaling genes leading to the production of proinflammatory cytokines.
InvivoGen offers a large selection of human and mouse genes involved in the TLR pathways.
TLR and TLR-related genes are provided either native, cloned from the ATG to the Stop codon, or modified by addition of a tag and/or deletion to generate dominant negative variants.