TLR and Related Genes

Toll-Like Receptors interact with co-receptor molecules to recognize specific molecular patterns associated with microbial pathogens. Upon recognition, they induce distinct cellular responses that involve different adaptor proteins which in turn will activate a cascade of signaling genes leading to the production of proinflammatory cytokines.

InvivoGen offers a large selection of human and mouse genes involved in the TLR pathways.

TLR and TLR-related genes are provided either native, cloned from the ATG to the Stop codon, or modified by addition of a tag and/or deletion to generate dominant negative variants.

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