TLR7

Expression-ready ORF Clones

Alias : TLR7

Toll Like Receptor 7

TLR7 is abundantly expressed in lung, placenta, spleen and BPL [1]. It is phylogenetically close to TLR8 and TLR9 and has a higher molecular weight when compared with hTLR1-6, largely as a result of a longer ectodomain [2]. TLR7 recognizes single stranded RNAs and small synthetic molecules such as imidazoquinolines and nucleoside analogs [3].

1. Zarember et al. (2002). J Immunol, 168(2):554-61.
2. Chuang & Ulevitch. (2000). Eur Cytokine Netw, 11(3):372-8.
3. Hemmi et al. (2002). Nat Immunol, 3(2):196-200.