pFUSE-Fc | Fc-fusion protein expression plasmids

Engineered Fc Region

Engineered pFUSE-Fc express mutant forms of the constant Fc regions of the human or murine IgG. They contain a multiple cloning site (MCS) upstream of these regions to enable the cloning of a gene of interest. Engineered Fc allow the production of IgG with modified effector function.

Learn more info on Engineered Fc Regions

Engineered Fc pFUSE-Fc Vectors

Human

(24)

pFUSE-hIgG1e1-Fc

Fc-fusion protein expression plasmid - Engineered human IgG1, increased half-life

2 products from $744

pFUSE-hIgG1e2-Fc

Fc-fusion protein expression plasmid - Engineered human IgG1, increased half-life

2 products from $744

pFUSE-hIgG1e4-Fc

Fc-fusion protein expression plasmid - Engineered human IgG1, increased ADCC and CDC

2 products from $744

pFUSE-hIgG1e5-Fc

Fc-fusion protein expression plasmid - Engineered human IgG1, increased ADCC

2 products from $744

pFUSE-hIgG1e6-Fc

Fc-fusion protein expression plasmid - Engineered human IgG1, unchanged half-life

2 products from $744

pFUSE-hIgG1e7-Fc

Fc-fusion protein expression plasmid - Engineered human IgG1, increased CDC

2 products from $744

pFUSE-hIgG1e9-Fc

Fc-fusion protein expression plasmid - Engineered human IgG1, increased macrophage phagocytosis

2 products from $744

pFUSE-hIgG1e11-Fc

Fc-fusion protein expression plasmid - Engineered human IgG1, increased half-life

2 products from $744

pFUSE-hIgG1e12-Fc

Fc-fusion protein expression plasmid - Engineered human IgG1, increased half-life

2 products from $744

pFUSE-hIgG1e13-Fc

Fc-fusion protein expression plasmid - Engineered human IgG1, decreased half-life

2 products from $744

pFUSE-hIgG2e1-Fc

Fc-fusion protein expression plasmid - Engineered human IgG2, reduced CDC

2 products from $744

pFUSE-hIgG4e1-Fc

Fc-fusion protein expression plasmid - Engineered human IgG4, reduced Fab-arm exchange

2 products from $744

Mouse

(4)

pFUSE-mIgG1e2-Fc

Fc-fusion protein expression plasmid - Engineered murine IgG1, increased protein A affinity

2 products from $744

pFUSE-mIgG2Ae1-Fc

Fc-fusion protein expression plasmid - Engineered murine IgG2a, reduced ADCC and CDC

2 products from $744