pFUSEN-hG1e2Fc

Engineered Fc Regions

ABOUT

pFUSEN-hG1e2Fc is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the mutated human IgG1 heavy chain and the hinge region fused to the N-terminus of a protein of interest..

The engineered hIgG1e2 Fc contains the following mutations: M252Y/S254T/T256E and H433K/N434F.

Human IgG1e2-Fc contains mutations in the site of interaction of IgG1 with FcRn that enhance the plasma half-life by increasing the affinity of IgG1 for FcRn.

All products are for research use only, and not for human or veterinary use.

SPECIFICATIONS

Specifications

Applications

Transient or stable transfection in vitro

Specificity

Human

Tag
Fc, N-ter
Antibiotic resistance
Zeocin®
Appearance (form)
Translucent film
Appearance (color)
Colorless
Reconstitution buffer
Sterile water (not provided)
Quality control

Plasmid construct has been confirmed by restriction analysis and sequencing.

CONTENTS

Contents

  • Product: 
    pFUSEN-hG1e2Fc
  • Cat code: 
    pfcn-hg1e2
  • Quantity: 
    20 µg

Shipping & Storage

  • Shipping method:  Room temperature

    • Storage:

    • 4°C or -20°C

DOCUMENTS

Documents

pFUSEN-hG1e2Fc

Technical Data Sheet

Safety Data Sheet

Certificate of analysis

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