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TLR05

pUNO1-bTLR05 Unit size Cat. code Docs Qty Price
pUNO1 bearing the bovine TLR5 gene
20 µg
puno1-btlr5
+-
$384.00
pUNO1-hTLR05 Unit size Cat. code Docs Qty Price
pUNO1 bearing the human TLR5 gene
20 µg
puno1-htlr5
+-
$384.00
pUNO3-hTLR05 Unit size Cat. code Docs Qty Price
pUNO3 bearing the human TLR5 gene
20 µg
puno3-htlr5
+-
$384.00
pUNO1-mTLR05 Unit size Cat. code Docs Qty Price
pUNO1 bearing the mouse TLR5 gene
20 µg
puno1-mtlr5
+-
$384.00
pUNO1-pTLR05 Unit size Cat. code Docs Qty Price
pUNO1 bearing the pig TLR5 gene
20 µg
puno1-ptlr5
+-
$384.00

Expression-ready ORF Clones

Alias : TLR5, CD285

Toll Like Receptor 5

TLR5 is the Toll-like molecule that recognizes flagellin from both Gram-positive and Gram-negative bacteria. TLR5 was identified by the presence of the TIR domain and is expressed in spleen, peripheral blood leukocytes and epithelial cells.
Activation of the receptor stimulates the production of proinflammatory cytokines, such as TNF-α, through signaling via the adaptor protein MyD88 and the serine kinase IRAK [1, 2]. TLR5 can generate a proinflammatory signal as a homodimer suggesting that it might be the only TLR required for flagellin recognition [2].

 

1. Gewirtz AT. et al. (2001). J Immunol, 167(4):1882-5.
2. Hayashi F. et al. (2001). Nature, 410(6832):1099-103.

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Specifications

Bovine TLR5 (pUNO1-bTLR05)

ORF size : 2577 bp
Subclone : NcoI - NheI

Human TLR5 (pUNO1-hTLR05)

Genbank : NM_003268.6
ORF size : 2577 bp
Subclone : NcoI - NheI

Human TLR5 (pUNO3-hTLR05)

ORF size : 2577 bp
Subclone : NcoI - NheI

Mouse TLR5 (pUNO1-mTLR05)

ORF size : 2580 bp
Subclone : AgeI - NheI

Pig TLR5 (pUNO1-pTLR05)

ORF size : 2571 bp
Subclone : AgeI - NheI

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Contents

pUNO1-bTLR05, pUNO1-hTLR05, pUNO1-mTLR05, pUNO1-pTLR05:
- 20 µg of lyophilized DNA.
- 4 pouches of E. coli Fast-Media® Blas (2 TB and 2 Agar)
- 1 ml blasticidin at 10 mg/ml

pUNO3-hTLR05:
- 20 µg of lyophilized DNA.
- 1 ml Hygromycin B Gold (hygromycin) at 100 mg/ml

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