Recombinant human IFN-γ
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Recombinant Cytokine, source: E. coli
Recombinant human interferon gamma (with HSA)
Interferon-gamma (IFN-γ), a Type II interferon, is secreted from CD4+ T-helper 1 (Th1) cells and activated natural killer (NK) cells. It plays a role in activating lymphocytes to enhance anti-microbial and anti-tumor effects. In addition, IFN-γ plays a role in regulating the proliferation, differentiation, and response of lymphocyte subsets.
Recombinant human IFN-γ (rhIFN-γ) produced in Escherichia coli is a single, non-glycosylated, polypeptide chain containing 144 amino acids and having a molecular mass of 16879 Daltons.
rhIFN-γ is used to induce its cognate signalling pathway in HEK-Blue™ IFN-γ cells.Back to the top
Source: E. coli
Uniprot ID: P01579
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS (pH 7.4) with human serum albumin (HSA) as a carrier protein
Purity: >95%, by SDS-PAGE
Molecular mass: ~ 16.8 kDa
Solubility: 100 μg/ml in water
Endotoxin level: < 0.1 EU/μg protein as determined by the LAL method
Bioactivity: Validated using HEK-Blue IFN-γ cellsBack to the top
Recombinant human IFN-γ is provided as a white lyophilized powder.
- 20 μg of recombinant human IFN-γ provided as a white lyophilized powder.
- 1.5 ml endotoxin-free water.
Recombinant human IFN-γ is shipped at room temperature.
Upon receipt it should be stored at -20°C.Back to the top