Recombinant human CD40L
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Recombinant Cytokine, source: E. coli
Recombinant Human CD40 Ligand (with HSA)
CD40 ligand, CD40L (also known as CD154, TRAP or gp39), is a type II transmembrane glycoprotein belonging to the TNF family.
CD40L is predominantly expressed on activated CD4+ T lymphocytes and interacts with CD40 on antigen-presenting cells to regulate both humoral and cellular immune responses.
Recombinant human CD40L (rhCD40L) is a 149 amino acid, non-glycosylated protein. The approximate molecular mass of CD40L is 16.3 kDa. CD40L is produced in Escherichia coli.
rhCD40L is used to induce its cognate signalling pathway in HEK-Blue™ CD40L cells.Back to the top
Source: E. coli
Uniprot ID: P29965
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS (pH 7.0) with human serum albumin (HSA) as a carrier protein
Purity: >95%, by SDS-PAGE
Molecular mass: ~ 16 kDa
Solubility: 100 μg/ml in water
Endotoxin level: < 0.1 EU/μg protein as determined by the LAL method
Bioactivity: Validated using HEK-Blue CD40L cellsBack to the top
Recombinant human CD40L is provided as a white lyophilized powder.
- 10 μg of recombinant human CD40L
- 1.5 ml endotoxin-free water.
Recombinant human CD40L is shipped at room temperature.
Upon receipt it should be stored at -20 °C.Back to the top