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#TLR7/8 Ligands

R848 (Resiquimod) - TLR7/8 Agonist

Imidazoquinoline compound - CAS #144875-48-9

NF-κB response of HEK-Blue™-derived cells to R848

NF-κB and IRF responses of THP1-Dual™-derived cells to R848

R848 chemical structure

HKST - TLR2/TLR4 Agonist

Heat Killed Salmonella typhimurium

HKST dose-dependent activation of TLR2 and TLR4

#TLR7/8 Ligands

TL8-506 - TLR8 Agonist

Benzo-azepine analog - CAS #1268163-15-0

NF-κB response of HEK-Blue™-derived cells to TL8-506

NF-κB and IRF responses of THP1-Dual™-derived cells to TL8-506

#TLR-NOD (Kits) Ligands

Mouse TLR9 Agonist Kit

Set of known agonists for mouse TLR9

Dose-dependent NF-κB response of ODN 1585 in HEK-Blue™ mTLR9 cells

NF-κB response of ODN 1826 in HEK-Blue™-derived cells

NF-κB response in HEK-Blue™-derived cells upon ODN 2395 stimulation

#TLR-NOD (Kits) Ligands

Human TLR9 Agonist Kit

Set of known agonists for human TLR9

Dose-dependent NF-κB response of ODN 2216 in HEK-Blue™ hTLR9 cells

Dose-dependent NF-κB response in HEK-Blue™ hTLR9 cells.

NF-κB responses in HEK-Blue™ mTLR9 cells

#TLR-NOD (Kits) Ligands

Human TLR3/7/8/9 Agonist kit

14 ligands for human TLR3, TLR7, TLR8 and TLR9

Response of HEK-Blue™-derived cells to TLR3 agonists

NF-κB response of HEK-Blue™-derived cells to R848

NF-κB response of HEK-Blue™-derived cells to ssRNA40/LyoVec™

Dose-dependent NF-κB response in HEK-Blue™ hTLR9 cells.

#TLR-NOD (Kits) Ligands

Mouse TLR1-9 Agonist kit

9 ligands for murine TLR1 to TLR9

Evaluation of NF-κB activation with Pam3CSK4

Dose-dependent activation of TLR3

LPS-EK Standard-dependent activation of TLR2 and TLR4

NF-κB response of ODN 1826 in HEK-Blue™-derived cells

#TLR-NOD (Kits) Ligands

Human TLR1-9 Agonist kit

10 ligands for human TLR1 to TLR9

Dose-dependent activation of TLR2 by FSL-1

Dose-dependent activation of TLR3

LPS-EK Standard-dependent activation of TLR2 and TLR4

NF-κB response induced by ODN 2006

#TLR7/8 Ligands

ssPolyU Naked - TLR8 Agonist

RNA homopolymer

NF-κB response of HEK-Blue™-derived cells to ssPolyU Naked

#TLR7/8 Ligands

ORN06/LyoVec™ - TLR7/8 Agonist

UUGU ssRNA polymer / LyoVec™ complexed

NF-κB response of HEK-Blue™-derived cells to ORN06/LyoVec™

Pam3CSK4 Biotin - TLR2/TLR1 Agonist

Biotinylated Synthetic triacylated lipopeptide

Pam3CSK4 Biotin dose-dependent activation of TLR2

Pam3CSK4 - TLR2/TLR1 Agonist

Synthetic triacylated lipopeptide

Evaluation of NF-κB activation with Pam3CSK4

Specificity of Pam3CSK4 activation

Pam2CSK4 - TLR2/TLR6 Agonist

Synthetic diacylated lipopeptide

Discrimination of TLR1-TLR2 and TLR2-TLR6 activation with synthetic ligands and heat-killed bacteria

FSL-1 - TLR2/TLR6 Agonist

Synthetic diacylated lipoprotein

Dose-dependent activation of TLR2 by FSL-1

PGN-SA peptidoglycan preparation - TLR2 Agonist

PGN from Staphylococcus aureus

PGN-SA dose-dependent activation of TLR2

PGN-BS peptidoglycan preparation - TLR2 Agonist

PGN from Bacillus subtilis

Response of HEK-Blue™ hTLR2 to TLR2 agonists

LTA-SA - TLR2 Agonist

LTA from S. aureus

Response of HEK-Blue™ hTLR2 to TLR2 agonists

HKSP - TLR2 Agonist

Heat Killed - Streptococcus pneumoniae

HKSP dose-dependent activation of TLR2

HKSA - TLR2 Agonist

Heat Killed - Staphylococcus aureus

HKSA dose-dependent activation of TLR2

#TLR7/8 Ligands

Loxoribine - TLR7 Agonist

Guanosine analog - CAS #121288-39-9

NF-κB response of HEK-Blue™-derived cells to loxoribine