Pam3CSK4 Biotin - TLR2/TLR1 Agonist

Biotinylated Synthetic triacylated lipopeptide

ABOUT

Biotinylated synthetic triacylated lipopeptide

Pam3CSK4 is a synthetic triacylated lipopeptide (LP) that mimics the acylated amino terminus of bacterial LPs.

Pam3CSK4 is a potent activator of the proinflammatory transcription factor NF-κB.

Activation is mediated by the interaction between TLR2 and TLR1 which recognize LPs with three fatty acids, a structural characteristic of bacterial LPs.

All products are for internal research use only, and not for human or veterinary use.

SPECIFICATIONS

Specifications

Source
Synthetic
Synonyms
P3C-SKKKK(Aca-Aca-Biotin) x 2TFA
Target

TLR2, TLR1

Chemical formula

C103H192N14O17S2 •2 TFA

Molecular weight
1962.9 g/mol
Working concentration

10 - 300 ng/ml

Solubility

100 µg/ml in water

Appearance (form)
Lyophilized
Reconstitution buffer
Endotoxin-free water (provided)
Endotoxin

Negative (tested using EndotoxDetect™ assay)

Tested applications

Cellular assays

Quality control

Each lot is functionally tested and validated.

CONTENTS

Contents

  • Product: 
    Pam3CSK4 Biotin
  • Cat code: 
    tlrl-bpms
  • Quantity: 
    50 µg
Includes:

1.5 ml endotoxin-free water

Shipping & Storage

  • Shipping method:  Room temperature

    • Storage:

    • -20°C

    Caution:

    • Avoid repeated freeze-thaw cycles
    • Protect from light

DOCUMENTS

Documents

Pam3CSK4 Biotin

Technical Data Sheet

Safety Data Sheet

Certificate of analysis

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