Human TLR3/7/8/9 Agonist kit

14 ligands for human TLR3, TLR7, TLR8 and TLR9

ABOUT

14 ligands for human TLR3, TLR7, TLR8 and TLR9

This Toll-like Receptor (TLR) agonist kit represents a convenient and economical tool to study the stimulation of the TLRs.

This kit contains several known TLR agonists:

and allows to perform up to 100 tests (in a 96-well plate).

 

All products are for research use only, and not for human or veterinary use.

SPECIFICATIONS

Specifications

Source
Synthetic
Target

TLR3, TLR7, TLR8, TLR9

Target species

Human

Sequence

ODN 2006: 5’-tcgtcgttttgtcgttttgtcgtt-3’ 
ODN 2216: 5’-ggGGGACGA:TCGTCgggggg-3’ 
ODN 2395: 5’-tcgtcgttttcggcgc:gcgccg-3’

ODN 2006 Control: 5’-tgctgcttttgtgcttttgtgctt-3’ 
ODN 2216 Control: 5’-ggGGGAGCA:TGCTGgggggc-3’ 
ODN 2395 Control: 5’-tgctgcttttggggggcccccc-3’ 

Note: Bases shown in capital letters are phosphodiester, those in lower case are phosphorothioate (nuclease resistant) and palindrome is in bold.

Working concentration

See TDS

Solubility

See TDS

Appearance (form)
Lyophilized
Reconstitution buffer
Endotoxin-free water (provided)
Tested applications

PRR cellular assays

Applications

TLR activation

Quality control

Each lot is functionally tested and validated using cellular assays.

CONTENTS

Contents

  • Product: 
    Human TLR3/7/8/9 Agonist kit (14 ligands)
  • Cat code: 
    tlrl-kit3hw3
  • Quantity: 
    1 kit
Includes:

TLR3 Agonist: Poly(I:C) (HMW) (500 µg)
TLR3 Agonist: Poly(I:C) (LMW) (500 µg)
TLR3 Agonist Poly(A:U) (500 µg)
TLR7 Agonist: Imiquimod (25 µg)
TLR7/8 Agonist: R848 (25 µg)
TLR7/8 Agonist: CL075 (25 µg)
hTLR8 Agonist: ssRNA40/LyoVec (25 µg)
ssRNA Control:ssRNA41/LyoVec(25 µg)
TLR9 Agonist: ODN2006(100 µg)
Control: ODN2006 control (100 µg)
TLR9 Agonist: ODN2216 (100 µg)
Control: ODN2216 control (100 µg)
TLR9 Agonist: ODN 2395 (100 µg)
Control: ODN 2395 control (100 µg)
2x 2 ml endotoxin-free water

Shipping & Storage

  • Shipping method:  Room temperature

    • Storage:

    • 4°C or -20°C according to the product label
    Stability: See TDS

    Caution:

    • Avoid repeated freeze-thaw cycles

DOCUMENTS

Documents

Human TLR3/7/8/9 Agonist kit (14 ligands)

Technical Data Sheet

Safety Data Sheet

Certificate of analysis

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