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VET-SAP® saponin adjuvant

Saponin vaccine adjuvant - CAS #8047-15-2

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Poly(dA:dT) Rhodamine - RIG-I & CDS Agonist, AIM2 Inflammasome Inducer

Rhodamine labeled

Dose-dependent interferon regulatory factor (IRF) response to transfected Poly(dA:dT) Rhodamine in A549-Dual™ cells.

CL429 VacciGrade™ - TLR2 & NOD2-based Adjuvant

Pam2C-conjugated murabutide

Dose-dependent NF-κB response to CL429 in HEK-Blue™ hTLR2 and HEK-Blue™ hNOD2 cells

CL429 chemical structure

Pam3CSK4 VacciGrade™ - TLR2/TLR1-based Adjuvant

Synthetic triacylated lipopeptide | Th1 response

Evaluation of NF-κB activation with Pam3CSK4

Specificity of Pam3CSK4 activation

ODN 1585 VacciGrade™ - TLR9-based Adjuvant

CpG ODN, Class A (Mouse) | Th1 response

Dose-dependent NF-κB response of ODN 1585 in HEK-Blue™ mTLR9 cells

NF-κB and IRF responses of ODN 1585 in THP1-Dual™ hTLR9 cells

M-TriLYS - NOD2 Agonist

Synthetic muramyl tripeptide

M-TriLYS dose-dependent activation of NOD2

CL413 VacciGrade™ - TLR2 & TLR7-based Adjuvant

Chimeric molecule | Th1/Th2 response

Tumor growth after CL413 or CL401 treatment

Survival curves for untreated as well as CL413- or CL401-treated mice

CL413 chemical structure

CL401 VacciGrade™ - TLR2 & TLR7-based Adjuvant

Pam2C-conjugated 8-hydroxyadenine| Th1/Th2 response

Tumor growth after CL413 or CL401 treatment

Survival curves for untreated as well as CL413- or CL401-treated mice

Anti-OVA mIgG levels at 15, 30 and 45 days after the initial immunization in different groups.

Anti-OVA total IgG, IgG1, and IgG2a levels 45 days after the initial immunization in different groups.

Quil-A® adjuvant

Saponin vaccine adjuvant

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DMXAA - STING Ligand

Vadimezan, ASA404, murine STING ligand

NF-kB activation (SEAP reporter)

IRF activation (Lucia luciferase reporter)

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Poly(dG:dC) - CDS Agonist

Naked or Complexed with Lyovec™

IRF response of RAW-Lucia™ ISG cells

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Poly(dA:dT) - RIG-I & CDS Agonist, AIM2 Inflammasome Inducer

Naked or Complexed with Lyovec™

Evaluation of inflammasome mediated-pyroptosis

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5'ppp-dsRNA Control - RIG-I Agonist Negative Control

Negative control for 5′ppp-dsRNA

RIG-I stimulation using 5’ppp-dsRNA and LyoVec™ in B16-Blue™ ISG cells

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5'ppp-dsRNA - RIG-I Agonist

5' triphosphate double stranded RNA - Naked or Complexed with Lyovec™

A549-Dual™ cellular response to 3p-hpRNA and 5`ppp-dsRNA

Cellular response to 3p-hpRNA and 5’ppp-dsRNA

PGN-SAndi ultrapure peptidoglycan - NOD2 Agonist

Insoluble peptidoglycan from S. aureus

Dose-dependent NF-κB response to PGN-SAndi Ultrapure in HEK-Blue™ hNOD2 cells

PGN-ECndss ultrapure peptidoglycan - NOD1/NOD2 Agonist

Soluble sonicated peptidoglycan from E. coli K12

Dose-dependent NF-κB response of PGN-ECndss Ultrapure in HEK-Blue™ hNOD1 and HEK-Blue™ hNOD2 cells

PGN-ECndi Ultrapure Peptidoglycan - NOD2 Agonist

Insoluble peptidoglycan from E. coli K12

Dose-dependent NF-κB response to PGN-ECndi Ultrapure in HEK-Blue™ hNOD1 and HEK-Blue™ hNOD2 cells

M-TriDAP - NOD1/NOD2 Agonist

MurNAc-L-Ala-gamma-D-Glu-mDAP - PGN-like molecule

NF-κB responses of HEK-Blue™ hNOD1 cells to various PRR agonists and cytokines

NF-kB response of HEK-Blue™ hNOD2 cells to various PRR agonists and cytokines

Murabutide - NOD2 Agonist

Synthetic derivative of muramyldipeptide

Murabutide dose-dependent activation of NOD2

N-Glycolyl-MDP - NOD2 Agonist

N-glycolylated muramyldipeptide

N-Glycolyl-MDP dose-dependent activation of NOD2