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N-Glycolyl-MDP

N-Glycolyl-MDP Unit size Cat. code Docs Qty Price
N-glycolylated muramyldipeptide
5 mg
tlrl-gmdp
+-
$189.00

NOD2 Agonist - N-glycolylated muramyldipeptide

The NOD2 agonist, MDP (muramyl dipeptide), is the minimal bioactive peptidoglycan motif common to all bacteria and the essential structure required for adjuvant activity in vaccines.

The cell wall of mycobacteria is extremely immunogenic and this potent activity is attributed to their MDP which is N-glycolylated in contrast to the MDP of most bacteria which is N-acetylated.

N-glycolyl-MDP displays strong NOD2-mediated activity and is considered a potent adjuvant.

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Specifications

Specificity: NOD2 agonist

Working Concentration: 100 ng  - 10 µg/ml

Solubility: 5 mg/ml in water

Formula: C19H32N4O12

Molecular weight: 508.48

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Contents

N-glycolyl-MDP is provided as a lyophilized powder.

  • 5 mg N-glycolyl-MDP
  • 1.5 ml sterile endotoxin-free water

room temperature N-glycolyl-MDP is shipped at room temperature.

store Store at -20°C. Upon resuspension, N-glycolyl-MDP should be aliquoted and stored at -20°C.

stable Lyophilized product is stable for 1 year at -20°C.  Resuspended product is stable for 6 months at -20°C when properly stored.

Alert Avoid repeated freeze-thaw cycles.

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