N-Glycolyl-MDP
| N-Glycolyl-MDP | Unit size | Cat. code | Docs | Qty | Price |
|---|---|---|---|---|---|
N-glycolylated muramyldipeptide |
5 mg |
tlrl-gmdp |
NOD2 Agonist - N-glycolylated muramyldipeptide
The NOD2 agonist, MDP (muramyl dipeptide), is the minimal bioactive peptidoglycan motif common to all bacteria and the essential structure required for adjuvant activity in vaccines.
The cell wall of mycobacteria is extremely immunogenic and this potent activity is attributed to their MDP which is N-glycolylated in contrast to the MDP of most bacteria which is N-acetylated.
N-glycolyl-MDP displays strong NOD2-mediated activity and is considered a potent adjuvant.
Back to the topSpecifications
Specificity: NOD2 agonist
Working Concentration: 100 ng - 10 µg/ml
Solubility: 5 mg/ml in water
Formula: C19H32N4O12
Molecular weight: 508.48
Back to the topContents
N-glycolyl-MDP is provided as a lyophilized powder.
- 5 mg N-glycolyl-MDP
- 1.5 ml sterile endotoxin-free water
N-glycolyl-MDP is shipped at room temperature.
Store at -20°C. Upon resuspension, N-glycolyl-MDP should be aliquoted and stored at -20°C.
Lyophilized product is stable for 1 year at -20°C. Resuspended product is stable for 6 months at -20°C when properly stored.
Avoid repeated freeze-thaw cycles.