Poly(dA:dT) Rhodamine
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Cat.code:
tlrl-patrh
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ABOUT
Rhodamine labeled double-stranded B-DNA
Poly(dA:dT) Rhodamine was chemically labeled by covalent coupling of a rhodamine probe containing a reactive alkylating group. This confers fluorescent properties to Poly(dA:dT) with a slight reduction of pattern recognition receptor (PRR) stimulatory activity.
Poly(dA:dT) is a poly(deoxyadenylic-deoxythymidylic) acid sodium salt and a repetitive double-stranded DNA (dsDNA) sequence of poly(dA-dT)•poly(dT-dA). Poly(dA:dT) is a synthetic analog of B-DNA.
Intracellular poly(dA:dT) is recognized by several cytosolic DNA sensors, triggering an immune response.
Furthermore, poly(dA:dT) is indirectly sensed by RIG-I leading to type I IFN production.
All products are for research use only, and not for human or veterinary use.
SPECIFICATIONS
Specifications
100 ng - 10 µg/ml
flow cytometry, fluorescent microscopy, confocal microscopy
Each lot is functionally tested and validated.
CONTENTS
Contents
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Product:Poly(dA:dT) Rhodamine
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Cat code:tlrl-patrh
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Quantity:10 µg
1.5 ml endotoxin-free water
Endotoxin level: Spectral properties of rhodamine:
Excitation λ max: 546 nm
Emission λ max: 576 nm
Shipping & Storage
- Shipping method: Room temperature
- -20°C
- Avoid repeated freeze-thaw cycles
- Protect from light
Storage:
Caution:
DOCUMENTS
Documents
Technical Data Sheet
Safety Data Sheet
Certificate of analysis
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