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#TLR7/8 Ligands

R848 (Resiquimod) - TLR7/8 Agonist

Imidazoquinoline compound - CAS #144875-48-9

NF-κB response of HEK-Blue™-derived cells to R848

NF-κB and IRF responses of THP1-Dual™-derived cells to R848

R848 chemical structure

#TLR7/8 Ligands

TL8-506 - TLR8 Agonist

Benzo-azepine analog - CAS #1268163-15-0

NF-κB response of HEK-Blue™-derived cells to TL8-506

NF-κB and IRF responses of THP1-Dual™-derived cells to TL8-506

#Antibiotics Selection

HEK-Blue™ CLR Selection

Antibiotics for maintenance of HEK-Blue™ Dectin & Mincle cells

Recommended use of HEK-Blue™ CLR Selection

ODN INH-18 - TLR9 Antagonist

Class B inhibitory ODN oligonucleotide

Dose-dependent inhibition of TLR9 activity by ODN INH-18.

ODN D-SL03 - TLR9 Agonist

CpG ODN, Class C (Multispecies)

Dose-dependent NF-κB response of ODN D-SL03 in HEK-Blue™ mTLR9 cells

ODN BW006 (ODN 684) - TLR9 Agonist

Stimulatory CpG ODN, Class B, Human/Mouse-preferred

Dose-dependent NF-κB response of ODN BW006 in HEK-Blue™ hTLR9 cells

ODN D-SL01 - TLR9 Agonist

CpG ODN, Class B (Multispecies)

Dose-dependent NF-κB response of ODN D-SL01 in HEK-Blue™ mTLR9 cells

#Antibiotics Selection

Zeocin®

Selective antibiotic for the Sh ble gene

Zeocin® by InvivoGen

#Antibiotics Selection

Puromycin

Selective antibiotic for the pac gene

Puromycin by InvivoGen

Chemical structure of Puromycin

#Antibiotics Selection

Phleomycin

Selective antibiotic for the Sh ble gene

Phleomycin by InvivoGen

#Antibiotics Selection

Hygromycin B Gold

Selective antibiotic for the hph gene

Hygromycin B Gold™ by InvivoGen

Chemical structure of Hygromycin

#Antibiotics Selection

G418 (Geneticin)

Selective antibiotic for the neo gene

G418 (Geneticin) by InvivoGen

Chemical structure of G418 (Geneticin)

#TLR7/8 Ligands

ssPolyU Naked - TLR8 Agonist

RNA homopolymer

NF-κB response of HEK-Blue™-derived cells to ssPolyU Naked

#TLR7/8 Ligands

ORN06/LyoVec™ - TLR7/8 Agonist

UUGU ssRNA polymer / LyoVec™ complexed

NF-κB response of HEK-Blue™-derived cells to ORN06/LyoVec™

ODN TTAGGG (A151) - TLR9 Antagonist

TLR9, AIM2, and cGAS antagonist

TLR9 signaling inhibition

Specific AIM2 inflammasome signaling inhibition

CDS signaling inhibition

ODN 4084-F - TLR9 Antagonist

Class B inhibitory ODN

Dose-dependent inhibition of TLR9 activity by ODN 4084-F

ODN 2088 control - TLR9 Ligand

Negative control for ODN 2088

Dose-dependent inhibition of TLR9 activity in HEK-Blue™ mTLR9 cells.

ODN 2088 - TLR9 Antagonist

Inhibitory ODN, preference towards mouse

Dose-dependent inhibition of TLR9 activity by ODN 2088

#TLR7/8 Ligands

Loxoribine - TLR7 Agonist

Guanosine analog - CAS #121288-39-9

NF-κB response of HEK-Blue™-derived cells to loxoribine

#TLR7/8 Ligands

Imiquimod (R837) - TLR7 Agonist

Imidazoquinoline compound - CAS #99011-78-6

NF-κB response of HEK-Blue™-derived cells to imiquimod

NF-κB and IRF responses of HEK-Dual™-derived cells to imiquimod