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M-TriLYS - NOD2 Agonist

Synthetic muramyl tripeptide

M-TriLYS dose-dependent activation of NOD2

#TLR-NOD (Kits) Ligands

Mouse TLR9 Agonist Kit

Set of known agonists for mouse TLR9

Dose-dependent NF-κB response of ODN 1585 in HEK-Blue™ mTLR9 cells

NF-κB response of ODN 1826 in HEK-Blue™-derived cells

NF-κB response in HEK-Blue™-derived cells upon ODN 2395 stimulation

#TLR-NOD (Kits) Ligands

Human TLR9 Agonist Kit

Set of known agonists for human TLR9

Dose-dependent NF-κB response of ODN 2216 in HEK-Blue™ hTLR9 cells

Dose-dependent NF-κB response in HEK-Blue™ hTLR9 cells.

NF-κB responses in HEK-Blue™ mTLR9 cells

#TLR-NOD (Kits) Ligands

Human TLR3/7/8/9 Agonist kit

14 ligands for human TLR3, TLR7, TLR8 and TLR9

Response of HEK-Blue™-derived cells to TLR3 agonists

NF-κB response of HEK-Blue™-derived cells to R848

NF-κB response of HEK-Blue™-derived cells to ssRNA40/LyoVec™

Dose-dependent NF-κB response in HEK-Blue™ hTLR9 cells.

#TLR-NOD (Kits) Ligands

Mouse TLR1-9 Agonist kit

9 ligands for murine TLR1 to TLR9

Evaluation of NF-κB activation with Pam3CSK4

Dose-dependent activation of TLR3

LPS-EK Standard-dependent activation of TLR2 and TLR4

NF-κB response of ODN 1826 in HEK-Blue™-derived cells

#TLR-NOD (Kits) Ligands

Human TLR1-9 Agonist kit

10 ligands for human TLR1 to TLR9

Dose-dependent activation of TLR2 by FSL-1

Dose-dependent activation of TLR3

LPS-EK Standard-dependent activation of TLR2 and TLR4

NF-κB response induced by ODN 2006

#Reporter Detection Reagents

HEK-Blue™ Detection - SEAP Detection Medium

Cell culture medium for real-time SEAP detection

HEK-Blue™ Detection by InvivoGen

PGN-SAndi ultrapure peptidoglycan - NOD2 Agonist

Insoluble peptidoglycan from S. aureus

Dose-dependent NF-κB response to PGN-SAndi Ultrapure in HEK-Blue™ hNOD2 cells

PGN-ECndss ultrapure peptidoglycan - NOD1/NOD2 Agonist

Soluble sonicated peptidoglycan from E. coli K12

Dose-dependent NF-κB response of PGN-ECndss Ultrapure in HEK-Blue™ hNOD1 and HEK-Blue™ hNOD2 cells

PGN-ECndi Ultrapure Peptidoglycan - NOD2 Agonist

Insoluble peptidoglycan from E. coli K12

Dose-dependent NF-κB response to PGN-ECndi Ultrapure in HEK-Blue™ hNOD1 and HEK-Blue™ hNOD2 cells

M-TriDAP - NOD1/NOD2 Agonist

MurNAc-L-Ala-gamma-D-Glu-mDAP - PGN-like molecule

NF-κB responses of HEK-Blue™ hNOD1 cells to various PRR agonists and cytokines

NF-kB response of HEK-Blue™ hNOD2 cells to various PRR agonists and cytokines

Murabutide - NOD2 Agonist

Synthetic derivative of muramyldipeptide

Murabutide dose-dependent activation of NOD2

N-Glycolyl-MDP - NOD2 Agonist

N-glycolylated muramyldipeptide

N-Glycolyl-MDP dose-dependent activation of NOD2

L18-MDP - NOD2 Agonist

Muramyldipeptide with a C18 fatty acid chain

L18-MDP dose-dependent activation of NOD2

MDP Control - NOD2 Agonist Negative Control

Negative control for MDP - Muramyldipeptide (L-L isomer, inactive)

Dose-dependent NF-κB response in HEK-Blue™ hNOD2 cells

MDP - NOD2 Agonist

Muramyl dipeptide (L-D isomer)

MDP dose-dependent activation of NOD2

Tri-DAP - NOD1 Agonist

L-Ala-gamma-D-Glu-mDAP

Tri-DAP dose-dependent activation of NOD1

C12-iE-DAP - NOD1 Agonist

Acylated derivative of iE-DAP

C12-iE-DAP dose-dependent activation of NOD1

iE-DAP - NOD1 Agonist

D-gamma-Glu-mDAP

Dose-dependent NF-κB responses of HEK-Blue™ hNOD1 cells to NOD1-specific ligands

#Reporter Detection Reagents

QUANTI-Luc™: Luciferase Detection Reagent

Luminescence detection kit for standard and HTS assays

Lucia luciferase detection for 10 min using QUANTI-Luc™ 4 Lucia/Gaussia

Lucia luciferase end-point detection using QUANTI-Luc™ 4 Lucia/Gaussia

Renilla luciferase detection for 20 min using QUANTI-Luc™ 4 Renilla

Renilla luciferase end-point detection using QUANTI-Luc™ 4 Renilla