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#Inflammasome Ligands

Cholesterol Crystals - NLRP3 Inflammasome Inducer

CAS number 57-88-5

Cholesterol Crystals structure invivogen

Microscopic analysis of Cholesterol Crystals

NLRP3 inflammasome activation by cholesterol crystals

#RLR and CDS Ligands

Poly(dA:dT) Rhodamine - RIG-I & CDS Agonist, AIM2 Inflammasome Inducer

Rhodamine labeled

Dose-dependent interferon regulatory factor (IRF) response to transfected Poly(dA:dT) Rhodamine in A549-Dual™ cells.

#Inflammasome Ligands

Nano-SiO2 - NLRP3 Inflammasome Inducer

Silica dioxide nanoparticles

Evaluation of NLRP3 inflammasome activation with Nano-SiO2

#TLR-NOD (Kits) Ligands

Mouse TLR9 Agonist Kit

Set of known agonists for mouse TLR9

Dose-dependent NF-κB response of ODN 1585 in HEK-Blue™ mTLR9 cells

NF-κB response of ODN 1826 in HEK-Blue™-derived cells

NF-κB response in HEK-Blue™-derived cells upon ODN 2395 stimulation

#TLR-NOD (Kits) Ligands

Human TLR9 Agonist Kit

Set of known agonists for human TLR9

Dose-dependent NF-κB response of ODN 2216 in HEK-Blue™ hTLR9 cells

Dose-dependent NF-κB response in HEK-Blue™ hTLR9 cells.

NF-κB responses in HEK-Blue™ mTLR9 cells

#RLR and CDS Ligands

DMXAA - STING Ligand

Vadimezan, ASA404, murine STING ligand

NF-kB activation (SEAP reporter)

IRF activation (Lucia luciferase reporter)

#TLR-NOD (Kits) Ligands

Human TLR3/7/8/9 Agonist kit

14 ligands for human TLR3, TLR7, TLR8 and TLR9

Response of HEK-Blue™-derived cells to TLR3 agonists

NF-κB response of HEK-Blue™-derived cells to R848

NF-κB response of HEK-Blue™-derived cells to ssRNA40/LyoVec™

Dose-dependent NF-κB response in HEK-Blue™ hTLR9 cells.

#TLR-NOD (Kits) Ligands

Mouse TLR1-9 Agonist kit

9 ligands for murine TLR1 to TLR9

Evaluation of NF-κB activation with Pam3CSK4

Dose-dependent activation of TLR3

LPS-EK Standard-dependent activation of TLR2 and TLR4

NF-κB response of ODN 1826 in HEK-Blue™-derived cells

#TLR-NOD (Kits) Ligands

Human TLR1-9 Agonist kit

10 ligands for human TLR1 to TLR9

Dose-dependent activation of TLR2 by FSL-1

Dose-dependent activation of TLR3

LPS-EK Standard-dependent activation of TLR2 and TLR4

NF-κB response induced by ODN 2006

#RLR and CDS Ligands

Poly(dG:dC) - CDS Agonist

Naked or Complexed with Lyovec™

IRF response of RAW-Lucia™ ISG cells

#RLR and CDS Ligands

Poly(dA:dT) - RIG-I & CDS Agonist, AIM2 Inflammasome Inducer

Naked or Complexed with Lyovec™

Evaluation of inflammasome mediated-pyroptosis

#RLR and CDS Ligands

5'ppp-dsRNA Control - RIG-I Agonist Negative Control

Negative control for 5′ppp-dsRNA

RIG-I stimulation using 5’ppp-dsRNA and LyoVec™ in B16-Blue™ ISG cells

#RLR and CDS Ligands

5'ppp-dsRNA - RIG-I Agonist

5' triphosphate double stranded RNA - Naked or Complexed with Lyovec™

A549-Dual™ cellular response to 3p-hpRNA and 5`ppp-dsRNA

Cellular response to 3p-hpRNA and 5’ppp-dsRNA

#Inflammasome Ligands

CPPD Crystals - NLRP3 Inflammasome Inducer

Calcium Pyrophosphate Dihydrate crystals

Evaluation of inflammasome activation with CPPD crystals

#Inflammasome Ligands

MSU Crystals - NLRP3 Inflammasome Inducer

Monosodium Urate Crystals

Evaluation of inflammasome activation with MSU Crystals

#Inflammasome Ligands

Nigericin - NLRP3 Inflammasome Inducer

Nigericin sodium salt

Induction of IL-1β secretion by monocytes upon treatment with Nigericin

#Inflammasome Ligands

Hemozoin - NLRP3 Inflammasome Inducer

Synthetic heme crystal

Induction of IL-1β secretion by monocytes upon HZ treatment

#Inflammasome Ligands

ATP - NLRP3 Inflammasome Inducer

Adenosine 5'-triphosphate disodium salt

Induction of IL-1β secretion by monocytes upon HZ treatment

#RLR and CDS Ligands

dsDNA-EC - CDS & TLR9 Agonist

Double-stranded genomic DNA from E. coli K12

Dose-dependent interferon regulatory factor (IRF) response to transfected dsDNA-EC in THP1-Blue™ ISG cells.

#RLR and CDS Ligands

VACV-70c Control - CDS Agonist Negative Control

Control for CDS Ligand VACV-70

IRF response of RAW-Lucia™ ISG cells