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VET-SAP® saponin adjuvant

Saponin vaccine adjuvant - CAS #8047-15-2

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Poly(dA:dT) Rhodamine - RIG-I & CDS Agonist, AIM2 Inflammasome Inducer

Rhodamine labeled

Dose-dependent interferon regulatory factor (IRF) response to transfected Poly(dA:dT) Rhodamine in A549-Dual™ cells.

HKST - TLR2/TLR4 Agonist

Heat Killed Salmonella typhimurium

HKST dose-dependent activation of TLR2 and TLR4

CL429 VacciGrade™ - TLR2 & NOD2-based Adjuvant

Pam2C-conjugated murabutide

Dose-dependent NF-κB response to CL429 in HEK-Blue™ hTLR2 and HEK-Blue™ hNOD2 cells

CL429 chemical structure

Pam3CSK4 VacciGrade™ - TLR2/TLR1-based Adjuvant

Synthetic triacylated lipopeptide | Th1 response

Evaluation of NF-κB activation with Pam3CSK4

Specificity of Pam3CSK4 activation

ODN 1585 VacciGrade™ - TLR9-based Adjuvant

CpG ODN, Class A (Mouse) | Th1 response

Dose-dependent NF-κB response of ODN 1585 in HEK-Blue™ mTLR9 cells

NF-κB and IRF responses of ODN 1585 in THP1-Dual™ hTLR9 cells

CL413 VacciGrade™ - TLR2 & TLR7-based Adjuvant

Chimeric molecule | Th1/Th2 response

Tumor growth after CL413 or CL401 treatment

Survival curves for untreated as well as CL413- or CL401-treated mice

CL413 chemical structure

CL401 VacciGrade™ - TLR2 & TLR7-based Adjuvant

Pam2C-conjugated 8-hydroxyadenine| Th1/Th2 response

Tumor growth after CL413 or CL401 treatment

Survival curves for untreated as well as CL413- or CL401-treated mice

Anti-OVA mIgG levels at 15, 30 and 45 days after the initial immunization in different groups.

Anti-OVA total IgG, IgG1, and IgG2a levels 45 days after the initial immunization in different groups.

Quil-A® adjuvant

Saponin vaccine adjuvant

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DMXAA - STING Ligand

Vadimezan, ASA404, murine STING ligand

NF-kB activation (SEAP reporter)

IRF activation (Lucia luciferase reporter)

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Poly(dG:dC) - CDS Agonist

Naked or Complexed with Lyovec™

IRF response of RAW-Lucia™ ISG cells

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Poly(dA:dT) - RIG-I & CDS Agonist, AIM2 Inflammasome Inducer

Naked or Complexed with Lyovec™

Evaluation of inflammasome mediated-pyroptosis

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5'ppp-dsRNA Control - RIG-I Agonist Negative Control

Negative control for 5′ppp-dsRNA

RIG-I stimulation using 5’ppp-dsRNA and LyoVec™ in B16-Blue™ ISG cells

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5'ppp-dsRNA - RIG-I Agonist

5' triphosphate double stranded RNA - Naked or Complexed with Lyovec™

A549-Dual™ cellular response to 3p-hpRNA and 5`ppp-dsRNA

Cellular response to 3p-hpRNA and 5’ppp-dsRNA

LPS-EB VacciGrade™ - TLR4-based Adjuvant

Lipopolysaccharide from E. coli 0111:B4 | Th1 response

LPS-EB Vaccigrade™-dependent activation of TLR4

TDB VacciGrade™ - Mincle-based Adjuvant

Synthetic analog of the cord factor | Th1 response

TDB dose-dependent activation of Mincle

ODN 2395 VacciGrade™ - TLR9-based Adjuvant

CpG ODN, Class C (Human/mouse) | Th1 response

NF-κB response in HEK-Blue™-derived cells upon ODN 2395 stimulation

NF-κB and IRF response upon ODN 2395 stimulation

CFA

Complete Freund’s Adjuvant | Th1 response

Anti-Ova mIgG levels at 15 and 30 days after the initial immunization with CFA

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dsDNA-EC - CDS & TLR9 Agonist

Double-stranded genomic DNA from E. coli K12

Dose-dependent interferon regulatory factor (IRF) response to transfected dsDNA-EC in THP1-Blue™ ISG cells.

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VACV-70c Control - CDS Agonist Negative Control

Control for CDS Ligand VACV-70

IRF response of RAW-Lucia™ ISG cells