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M-TriLYS - NOD2 Agonist

Synthetic muramyl tripeptide

M-TriLYS dose-dependent activation of NOD2

PGN-SAndi ultrapure peptidoglycan - NOD2 Agonist

Insoluble peptidoglycan from S. aureus

Dose-dependent NF-κB response to PGN-SAndi Ultrapure in HEK-Blue™ hNOD2 cells

PGN-ECndss ultrapure peptidoglycan - NOD1/NOD2 Agonist

Soluble sonicated peptidoglycan from E. coli K12

Dose-dependent NF-κB response of PGN-ECndss Ultrapure in HEK-Blue™ hNOD1 and HEK-Blue™ hNOD2 cells

PGN-ECndi Ultrapure Peptidoglycan - NOD2 Agonist

Insoluble peptidoglycan from E. coli K12

Dose-dependent NF-κB response to PGN-ECndi Ultrapure in HEK-Blue™ hNOD1 and HEK-Blue™ hNOD2 cells

M-TriDAP - NOD1/NOD2 Agonist

MurNAc-L-Ala-gamma-D-Glu-mDAP - PGN-like molecule

NF-κB responses of HEK-Blue™ hNOD1 cells to various PRR agonists and cytokines

NF-kB response of HEK-Blue™ hNOD2 cells to various PRR agonists and cytokines

Murabutide - NOD2 Agonist

Synthetic derivative of muramyldipeptide

Murabutide dose-dependent activation of NOD2

N-Glycolyl-MDP - NOD2 Agonist

N-glycolylated muramyldipeptide

N-Glycolyl-MDP dose-dependent activation of NOD2

L18-MDP - NOD2 Agonist

Muramyldipeptide with a C18 fatty acid chain

L18-MDP dose-dependent activation of NOD2

MDP Control - NOD2 Agonist Negative Control

Negative control for MDP - Muramyldipeptide (L-L isomer, inactive)

Dose-dependent NF-κB response in HEK-Blue™ hNOD2 cells

MDP - NOD2 Agonist

Muramyl dipeptide (L-D isomer)

MDP dose-dependent activation of NOD2

Tri-DAP - NOD1 Agonist

L-Ala-gamma-D-Glu-mDAP

Tri-DAP dose-dependent activation of NOD1

C12-iE-DAP - NOD1 Agonist

Acylated derivative of iE-DAP

C12-iE-DAP dose-dependent activation of NOD1

iE-DAP - NOD1 Agonist

D-gamma-Glu-mDAP

Dose-dependent NF-κB responses of HEK-Blue™ hNOD1 cells to NOD1-specific ligands

#Transfection reagents

LyoVec™

Lyophilized lipid-based transfection reagent

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#Transfection reagents

NATE™ - Transfection & Transduction Enhancer

NATE™ - nucleic acid transfection & transduction enhancer

Greater transient transfection efficiency (microscopy)

Greater transient transfection efficiency (folds)

Increased number of stable SEAP-expressing RAW 264.7 clones

Greater transduction efficiency (microscopy)

Greater transduction efficiency (folds)

ADP-Heptose (L-isomer) - ALPK1 ligand

Synthetic ADP-L-Heptose

Functional validation of ADP-Heptose

ADP-Heptose (D- and L-isomer) activity