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TDB - Mincle Agonist

Synthetic analog of the cord factor

TDB dose-dependent activation of Mincle

NF-κB response to various Mincle agonists in HEK-Blue™ hMincle cells

#TLR-NOD (Kits) Ligands

Mouse TLR9 Agonist Kit

Set of known agonists for mouse TLR9

Dose-dependent NF-κB response of ODN 1585 in HEK-Blue™ mTLR9 cells

NF-κB response of ODN 1826 in HEK-Blue™-derived cells

NF-κB response in HEK-Blue™-derived cells upon ODN 2395 stimulation

#TLR-NOD (Kits) Ligands

Human TLR9 Agonist Kit

Set of known agonists for human TLR9

Dose-dependent NF-κB response of ODN 2216 in HEK-Blue™ hTLR9 cells

Dose-dependent NF-κB response in HEK-Blue™ hTLR9 cells.

NF-κB responses in HEK-Blue™ mTLR9 cells

#TLR-NOD (Kits) Ligands

Human TLR3/7/8/9 Agonist kit

14 ligands for human TLR3, TLR7, TLR8 and TLR9

Response of HEK-Blue™-derived cells to TLR3 agonists

NF-κB response of HEK-Blue™-derived cells to R848

NF-κB response of HEK-Blue™-derived cells to ssRNA40/LyoVec™

Dose-dependent NF-κB response in HEK-Blue™ hTLR9 cells.

#TLR-NOD (Kits) Ligands

Mouse TLR1-9 Agonist kit

9 ligands for murine TLR1 to TLR9

Evaluation of NF-κB activation with Pam3CSK4

Dose-dependent activation of TLR3

LPS-EK Standard-dependent activation of TLR2 and TLR4

NF-κB response of ODN 1826 in HEK-Blue™-derived cells

#TLR-NOD (Kits) Ligands

Human TLR1-9 Agonist kit

10 ligands for human TLR1 to TLR9

Dose-dependent activation of TLR2 by FSL-1

Dose-dependent activation of TLR3

LPS-EK Standard-dependent activation of TLR2 and TLR4

NF-κB response induced by ODN 2006

HKCA - Dectin-1 Agonist

Heat-killed Candida albicans

HKCA dose-dependent activation of Dectin-1

NF-κB response to various Dectin-1 agonists in HEK-Blue™ hDectin-1a cells

Curdlan - Dectin-1 Agonist

Beta-1,3-glucan from Alcaligenes faecalis

Curdlan dose-dependent activation of Dectin-1

NF-κB response to various Dectin-1 agonists in HEK-Blue™ hDectin-1a cells

Partial structure of Curdlan

#Reporter Detection Reagents

HEK-Blue™ Detection - SEAP Detection Medium

Cell culture medium for real-time SEAP detection

HEK-Blue™ Detection by InvivoGen

Depleted Zymosan - Dectin-1 Agonist

Hot alkali–treated zymosan — Selective Dectin-1 agonist, depleted of TLR2 activity

Zymosan Depleted dose-dependent activation of Dectin-1

NF-κB response to various Dectin-1 agonists in HEK-Blue™ hDectin-1a cells

Furfurman - Dectin-2 Agonist

Malassezia furfur cell wall preparation

Furfurman dose-dependent activation of Dectin-2

Laminarin - Dectin-1 Ligand

Soluble beta-glucan from Laminaria digitata - Dectin-1 Antagonist or Agonist

Laminarin dose-dependent activation of Dectin-1a

NF-κB response to various Dectin-1 agonists in HEK-Blue™ hDectin-1a cells

Partial structure of Laminarin

#Reporter Detection Reagents

QUANTI-Luc™: Luciferase Detection Reagent

Luminescence detection kit for standard and HTS assays

Lucia luciferase detection for 10 min using QUANTI-Luc™ 4 Lucia/Gaussia

Lucia luciferase end-point detection using QUANTI-Luc™ 4 Lucia/Gaussia

Renilla luciferase detection for 20 min using QUANTI-Luc™ 4 Renilla

Renilla luciferase end-point detection using QUANTI-Luc™ 4 Renilla

#Reporter Detection Reagents

Recombinant Lucia® Luciferase Protein - Positive Control

Positive control for luciferase reporter assays

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#Reporter Detection Reagents

Recombinant SEAP Protein - Positive Control

Positive control for SEAP reporter assays

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#Reporter Detection Reagents

QUANTI-Blue™ - SEAP Detection Reagent

Alkaline phosphatase detection reagent

QUANTI-Blue™ Standard procedure

QUANTI-Blue™ High Throughput Screening (HTS) procedure

Zymosan - TLR2 & Dectin-1 Agonist

Cell wall preparation of S. cerevisiae

Zymosan dose-dependent activation of Dectin-1, TLR2, and TLR4

NF-κB response to various Dectin-1 agonists in HEK-Blue™ hDectin-1a cells

Whole Glucan Particles (WGP) - Dectin-1 Ligand

WGP Dispersible and WGP Soluble (Control)

WGP Dispersible dose-dependent activation of Dectin-1a

WGP Soluble dose-dependent activation of Dectin-1a

NF-κB response to various Dectin-1 agonists in HEK-Blue™ hDectin-1a cells

#Reporter Detection Reagents

QUANTI-Star™: ACP5 Detection Reagent

Acid phosphatase 5 (ACP5) detection reagent

QUANTI-Star™ 96-well procedure

β-GlcCer - Mincle Agonist

C24:1 Glucosyl(β) Ceramide

β-GlcCer dose-dependent activation of Mincle

NF-κB response to various Mincle agonists in HEK-Blue™ hMincle cells