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Recombinant human IL-23 protein - Bioactive cytokine

Recombinant cytokine, source: CHO cells

Recombinant human IL-23 detection by SDS-PAGE

Dose-response in HEK-Blue™ IL-23 cells to recombinant IL-23 cytokine

Neutralization of IL-12 and IL-23 signaling using Ustekinumab biosimilar

Recombinant human IL-10 protein - Bioactive cytokine

Recombinant cytokine, source: HEK cells

Human IL-10 detection by SDS-PAGE

Dose-response of HEK-Blue™ IL-10 cells to recombinant IL-10

Neutralization of IL-10 signaling using Anti-hIL-10-hIgG1 antibody

Recombinant human CD40L protein - Bioactive cytokine

Recombinant cytokine, source: CHO cells

CD40L detection by SDS-PAGE

Dose-response in HEK-Blue™ CD40 cells to human CD40L

Neutralization of CD40L signaling using Frexalimab biosimilar

Human TLR3 Antibody

Human IgG1 (clone mAb15) - Recombinant

Detection of TLR3 expression in HEK-Blue-derived cells using flow cytometry

Dose-dependent inhibition of TLR3 signaling using Anti-hTLR3-hIgG1

Recombinant human TPO protein - Bioactive cytokine

Recombinant cytokine, source: CHO cells

SDS-PAGE analysis of recombinant human (h)TPO

Dose-response of HEK-Blue™ TPO cells to recombinant human (h)TPO

Recombinant human EPO protein - Bioactive cytokine

Recombinant cytokine, source: CHO cells

SDS-PAGE analysis of recombinant human (h)EPO.

Dose-response of HEK-Blue™ EPO cells to recombinant EPO

Jurkat-Raji PD-1/PD-L2 Antagonist Assay (Bio-IC™)

Two cell line bioassay - B lymphocytes & NFAT-Lucia reporter T lymphocytes

Validation of human PD-1 expression by Jurkat-Lucia™ TCR-hPD-1 cells.

Validation of human PD-L1 and PD-L2 expression by Raji-APC-hPD-L2 cells

Activation of Jurkat-Lucia™ TCR-hPD-1 cells using Anti-hPD-1 biosimilar mAbs

Activation of Jurkat-Lucia™ TCR-hPD-1 cells using Anti-hPD-L1 or Anti-hPD-L2 mAbs, alone or in combination

Jurkat-Raji (PD-1/CTLA4)/PD-L1 Antagonist Assay (Bio-IC™)

Two cell line bioassay - B lymphocytes & NFAT-Lucia reporter T lymphocytes

Validation of human CD28, CTLA4, and PD-1 expression by Jurkat-Lucia™ TCR-hCTLA4-hPD-1 cells

Validation of human CD80 and PD-L1 expression by Raji-APC-hPDL1-derived cells

Activation of Jurkat-Lucia™ TCR-hCTLA4-hPD-1 cells using Anti-hPD-1 and Anti-hCTLA4 biosimilar mAbs, alone or in combination

Jurkat-Raji CTLA4/CD80 Antagonist Assay (Bio-IC™)

Two cell line bioassay - B lymphocytes & NFAT-Lucia reporter T lymphocytes

Validation of human CD28 and CTLA4 overexpression by Jurkat-Lucia™ TCR-hCTLA4 cells

Validation of endogenous human CD80 expression by Raji-APC-Null cells

ation of Jurkat-Lucia™ TCR-hCTLA4 cells using Anti-hCTLA4 biosimilar mAb

Recombinant human IL-15 protein - Bioactive cytokine

Recombinant cytokine, source: CHO cells

Recombinant human IL-15 detection by SDS-PAGE

HEK-Blue™ IL-2/IL-15 cellular response to recombinant human IL-15.

Recombinant human IL-13 protein - Bioactive cytokine

Recombinant cytokine, source: CHO cells

Recombinant human IL-13 detection by SDS-PAGE

Dose-response in HEK-Blue™ IL-4/IL-13 cells to recombinant IL-13 cytokine

Neutralization of cellular response to IL-13 using Dupilumab biosimilar

Mouse IFI16-KO Reporter RAW 264.7 Cells

IRF-Lucia reporter mouse macrophages

IRF induction in RAW-Lucia™ ISG-KO-IFI16

Mouse IRF3-KO Reporter RAW 264.7 Cells

IRF-Lucia reporter mouse macrophages

Validation of IRF3 knockout by PCR

Validation of IRF3 knockout by Western blot (Wes™)

IRF induction in RAW-Lucia™ ISG-KO-IRF3

Mouse cGAS-KO Reporter RAW 264.7 Cells

IRF-Lucia reporter mouse macrophages

Validation of cGAS knockout by PCR

Validation of cGAS knockout by Western blot (Wes™)

IRF induction in RAW-Lucia™ ISG-KO-cGAS

WDFY1

WD repeat and FYVE domain containing 1

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NF-κB and ISG Dual Reporter A549 Cells

NF-κB-SEAP & IRF-Lucia reporter lung carcinoma

NF-κB induction in A549-Dual™ cells

IRF induction in A549-Dual™ cells

NF-κB and ISG Dual Reporter HCT116 Cells

NF-κB-SEAP & IRF-Lucia reporter colorectal carcinoma

NF-κB induction in HCT116-Dual™ cells

IRF induction in HCT116-Dual™ cells

Human PD-1 (CD279) Antibody - Nivolumab IgG1 Isotype

Human IgG1

ADCC assay using various anti-human PD-1 (Nivolumab) antibody isotypes and Raji-hPD-1 target cells

Disruption of PD-1/PD-L1 inhibitory interaction using Anti-hPD-1 or Anti-hPD-L1 antibodies

Human PD-1 (CD279) Antibody - Nivolumab Biosimilar

Human IgG4 (S228P) - CAS #946414-94-4

ADCC assay using various anti-human PD-1 (Nivolumab) antibody isotypes and Raji-hPD-1 target cells

Anti-hEGFR-hIgG4 (S228P)

Human EGFR (cetuximab) antibody - Human IgG4 (S228P)

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