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#TLR7/8 Ligands

CL097 - TLR7/TLR8 Agonist

Imidazoquinoline compound - CAS #1026249-18-2

NF-κB response of HEK-Blue™-derived cells to CL097

NF-κB and IRF responses of THP1-Dual™-derived cells to CL097

#TLR7/8 Ligands

CL075 (3M002) - TLR7/TLR8 Agonist

Thiazoquinoline compound - CAS #256922-53-9

NF-κB response of HEK-Blue™-derived cells to CL075

NF-κB and IRF responses of HEK-Dual™-derived cells to CL075

#TLR7/8 Ligands

ssRNA41/LyoVec™ - Negative Control

ssRNA40 negative control / LyoVec™ complexed

NF-κB response of HEK-Blue™ hTLR8 cells to ssRNA41/LyoVec™

#TLR7/8 Ligands

ssRNA40/LyoVec™ - TLR7/8 Agonist

HIV-1-derived ssRNA / LyoVec™ complexed

NF-κB response of HEK-Blue™-derived cells to ssRNA40/LyoVec™

#TLR7/8 Ligands

ssPolyU/LyoVec™ - TLR8 Agonist

RNA homopolymer / LyoVec™ complexed

NF-κB response of HEK-Blue™-derived cells to ssPolyU/LyoVec™

#TLR7/8 Ligands

TL7-887 (maleimide) and TL7-975 (azido) - Conjugatable TLR7 Ligands

Conjugatable adenine analogs

Biological activity of TL7-887

Biological activity of Anti-TROP2/TL7-887 in co-cultures

Biological activity of TL7-975

Biological activity of TL7-975 conjugated to Anti-HER2-hIgG1

#RLR and CDS Ligands

G3-YSD Control - cGAS Agonist Negative Control

Control for cGAS Agonist G3-YSD

Evaluation of IRF induction

#RLR and CDS Ligands

G3-YSD - cGAS Agonist

Y-form DNA

Evaluation of IRF induction

Evaluation of signaling pathway

#RLR and CDS Ligands

VACV-70/ LyoVec™ - CDS Agonist

Synthetic vaccinia virus DNA analog - LyoVec™ complexed

IRF response of RAW-Lucia™ ISG cells

#RLR and CDS Ligands

3p-hpRNA - RIG-I Agonist

5’ triphosphate hairpin RNA

A549-Dual™ cellular response to 3p-hpRNA and 5`ppp-dsRNA

Cellular response to 3p-hpRNA and 5’ppp-dsRNA