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ODN 1585 - TLR9 Agonist

Stimulatory CpG ODN, Class A, Mouse-preferred

Dose-dependent NF-κB response of ODN 1585 in HEK-Blue™ mTLR9 cells

NF-κB and IRF responses of ODN 1585 in THP1-Dual™ hTLR9 cells

E. coli ssDNA / LyoVec™ - TLR9 Agonist

E. coli single stranded DNA / LyoVec™ complexed

Dose-dependent response of E. coli ssDNA/LyoVec™ in THP1-Blue™ ISG cells

ODN TTAGGG control - TLR9 Ligand

Negative control for ODN TTAGGG

Dose-dependent inhibition of TLR9 activity in HEK-Blue™ hTLR9 cells

ODN 1826 FITC - TLR9 Agonist

FITC-labeled CpG ODN, Class B, Mouse-preferred

Detection of ODN 1826 FITC

ODN 1826 Biotin - TLR9 Agonist

Biotin-labeled CpG ODN 1826, Class B, Mouse-preferred

Detection of ODN 1826 Biotin

Human RIG-I Dual Reporter HEK 293 Cells (TLR3 & MDA5 deficient)

NF-κB-SEAP and IRF-Lucia reporter cells

Validation of RIG-I overexpression (Western blot)

Functional validation of HEK-Dual™ RNA-derived cells (NF-κB responses)

Functional validation of HEK-Dual™ RNA-RIG-I cells (IRF responses)

IRF Dose responses of HEK-Dual™ RNA-hRIG-I cells

Human MDA5 Dual Reporter HEK 293 Cells (TLR3 & RIG-I deficient)

NF-κB-SEAP and IRF-Lucia reporter cells

Validation of MDA5 overexpression (Western blot)

Functional validation of HEK-Dual™ RNA-MDA5 cells (NF-κB response)

Functional validation of HEK-Dual™ RNA-MDA5 cells (IRF responses)

IRF Dose responses of HEK-Dual™ RNA-hMDA5 cells

ODN 1826 control (ODN 2138) - TLR9 Ligand

Negative control for ODN 1826

Dose-dependent NF-κB response in HEK-Blue™ mTLR9 cells.

ODN 1826 - TLR9 Agonist

Stimulatory CpG ODN, Class B, Mouse-preferred

NF-κB response of ODN 1826 in HEK-Blue™-derived cells

NF-κB and IRF responses of ODN 1826 in THP1-Dual™ hTLR9 cells

ODN 1668 - TLR9 Agonist

CpG ODN, Class B (Mouse)

Dose-dependent NF-κB response of ODN 1668 in HEK-Blue™ mTLR9 cells

ODN 2006 control (ODN 2137) - TLR9 Ligand

Negative control for ODN 2006

Dose-dependent NF-κB response in HEK-Blue™ hTLR9 cells.

ODN 2006 (ODN 7909) - TLR9 Agonist

Stimulatory CpG ODN, Class B, Human-preferred

Species-driven TLR9 differential responses

NF-κB response induced by ODN 2006

IRF response induced by ODN 2006

HEK-Blue™ KD-TLR5 Cells

TLR5 deficient - IL1-β SEAP reporter HEK293 cells

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Mouse TBK1-KO Reporter RAW 264.7 Cells

IRF-Lucia reporter mouse macrophages

Validation of TBK-1 knockout by Western blot (Wes™)

IRF induction in RAW-Lucia™ ISG-KO-TBK1

ODN 2395 control - TLR9 Ligand

Negative control for ODN 2395, Class C, Human/mouse-preferred

NF-κB responses in HEK-Blue™ mTLR9 cells

ODN 2395 - TLR9 Agonist

Stimulatory CpG ODN, Class C, Human/Mouse-preferred

NF-κB response in HEK-Blue™-derived cells upon ODN 2395 stimulation

NF-κB and IRF response upon ODN 2395 stimulation

ODN 2336 - TLR9 Agonist

CpG ODN, Class A (Human)

NF-κB and IRF responses induced by ODN 2336

Mouse NOD1 Reporter HEK 293 Cells

NF-κB-SEAP reporter cells

NF-κB responses of HEK-Blue™ mNOD1 cells to various PRR agonists and cytokines

Dose-dependent NF-κB responses of HEK-Blue™ mNOD1 cells to NOD1-specific ligands

Human NOD1 Reporter HEK 293 Cells

NF-κB-SEAP reporter cells

NF-κB responses of HEK-Blue™ hNOD1 cells to various PRR agonists and cytokines

Dose-dependent NF-κB responses of HEK-Blue™ hNOD1 cells to NOD1-specific ligands

ODN M362 - TLR9 Agonist

CpG ODN, Class C (Human/mouse)

Dose-dependent NF-κB response of ODN M362 in HEK-Blue™ mTLR9 cells