ODN 1826 Biotin
| ODN 1826 Biotin | Unit size | Cat. code | Docs | Qty | Price |
|---|---|---|---|---|---|
Class B - Biotin-labeled ODN 1826 |
2 x 50 µg |
tlrl-1826b |
Biotin labeled CpG oligonucleotide - Murine TLR9 ligand
ODN 1826 Biotin is a CpG ODN class B specific for murine TLR9.
ODN 1826 Biotin can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
CpG ODNs are synthetic oligonucleotides that contain unmethylated CpG dinucleotides in particular sequence contexts (CpG motifs).
These CpG motifs are present at a 20-fold greater frequency in bacterial DNA compared to mammalian DNA.
They have been shown to induce a coordinated set of immune responses based on the activation of immune cells primarily involved in the recognition of these molecules.
Back to the topSpecifications
Specificity: Human TLR9 agonist
Working concentration: 1-5 μM
ODN 1826 sequence : 5’-tccatgacgttcctgacgtt-3’ (20 mer)
Note: Bases are phosphorothioate (nuclease resistant).
Contents
- 2 x 50 μg (7.32 nmol) lyophilized ODN 1826 labeled with biotin at the 3’ terminus
- 1 ml sterile endotoxin-free water
ODN 1826 Biotin is shipped at room temperature.
Store at -20°C. Resuspended product should be stored at -20°C.
Lyophilized product is stable for 12 months. Resuspended product is stable for 6 months.
Avoid repeated freeze-thaw cycles.