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ODN 1826 Biotin

ODN 1826 Biotin Unit size Cat. code Docs Qty Price
Class B - Biotin-labeled ODN 1826
2 x 50 µg
tlrl-1826b
+-
$151.00

Biotin labeled CpG oligonucleotide - Murine TLR9 ligand

CpG   ODNs are synthetic oligonucleotides that contain unmethylated CpG   dinucleotides in particular sequence contexts (CpG motifs).

These CpG motifs are present at a 20-fold greater frequency in bacterial DNA compared to mammalian DNA.

They have been shown to induce a coordinated set of immune responses based on the activation of immune cells primarily involved in the recognition of these molecules.

ODN 1826 Biotin is a CpG ODN class B specific for murine TLR9.

ODN 1826 Biotin can  be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.

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Specifications

Specificity: Human TLR9 agonist

Working concentration: 1-5 μM

ODN 1826 sequence : 5’-tccatgacgttcctgacgtt-3’ (20 mer)
Note: Bases are phosphorothioate (nuclease resistant).

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Contents

  • 2 x 50 μg (7.32 nmol) lyophilized ODN 1826 labeled with biotin at the 3’ terminus
  • 1 ml sterile endotoxin-free water

room temperature ODN 1826 Biotin is shipped at room temperature.

store Store at -20°C. Resuspended product should be stored at -20°C.

stable Lyophilized product is stable for 12 months. Resuspended product is stable for 6 months.

Alert Avoid repeated freeze-thaw cycles.

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