THP1-Blue™ ISG Cells
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Cat.code:
thp-isg
- Documents
ABOUT
Interferon regulatory factor-inducible SEAP Reporter Monocytes
THP1-Blue™ ISG cells were specifically designed for monitoring the interferon signaling pathway in a physiologically relevant cell line. They were derived from the human THP-1 monocyte cell line by stable integration of an interferon regulatory factor (IRF)-inducible SEAP reporter construct.
As a result, THP1-Blue™ ISG cells allow the monitoring of IRF activation by determining the activity of SEAP. The levels of IRF-induced SEAP in the cell culture supernatant are readily assessed with QUANTI-Blue™, a SEAP detection reagent.
THP1-Blue™ ISG cells are highly responsive to PRR agonists that trigger the IFN signaling pathway, such as LPS and transfected double-stranded nucleic acid.
Disclaimer: These cells are for internal research use only and are covered by a Limited Use License (See Terms and Conditions). Additional rights may be available.
SPECIFICATIONS
Specifications
Screening of PRR agonists or inhibitors
Complete RPMI 1640 (see TDS)
Verified using Plasmotest™
Each lot is functionally tested and validated.
CONTENTS
Contents
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Product:THP1-Blue™ ISG Cells
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Cat code:thp-isg
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Quantity:3-7 x 10^6 cells
- 1 ml Normocin™ (50 mg/ml)
- 1 ml of Zeocin® (100 mg/ml)
- 1 ml of QB reagent and 1 ml of QB buffer (sufficient to prepare 100 ml of QUANTI-Blue™ Solution)
Shipping & Storage
- Shipping method: Dry ice
- Liquid nitrogen vapor
- Upon receipt, store immediately in liquid nitrogen vapor. Do not store cell vials at -80°C.
Storage:
Caution:
DOCUMENTS
Documents
Technical Data Sheet
Safety Data Sheet
Certificate of analysis
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