Inflammasome / Innate immunity

Inflammasomes are multimeric protein complexes that are crucial for host defense to infection and...
Innate immunity / PRR

Toll-Like Receptors (TLRs) play a critical role in the early innate immune response to invading...
Innate immunity / PRR

C-type lectin receptors (CLRs) comprise a large family of receptors that bind to carbohydrates in a...
Vaccination

The mucosal surfaces represent the largest area of exposure of the body to external pathogens...
Vaccination

Immunoglobulin G (IgG) antibodies are large molecules composed of two heavy chains γ and two light...
STING / Innate immunity / PRR

The innate immune system reacts to diverse molecules of microbial origin, termed pathogen-associated...
Innate immunity / PRR

Damage-associated molecular patterns (DAMPs), also known as alarmins, are molecules released by...
Antibodies

The Fc region of an antibody mediates its serum half-life and effector functions, such as complement...
Inflammasome / Innate immunity

The inflammasome is a large multiprotein complex which plays a key role in innate immunity by...