Pepinh-TRIF
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Cat.code:
tlrl-pitrif
- Documents
ABOUT
TRIF inhibitory peptide
Pepinh-TRIF is a 30 aa peptide that blocks TRIF signaling by interfering with TLR-TRIF interaction.
PepinhTRIF contains the 14 aa that correspond to the sequence of the BB loop of TRIF (FCEEFQVPGRGELH) [1] linked to the cell-penetrating segment of the antennapedia homeodomain (RQIKIWFQNRRMKWKK) [2].
Pepinh TRIF is provided with Pepinh-Control, a control peptide [1].
References:
1. Toshchakov V. et al., 2005. Differential Involvement of BB Loops of Toll-IL-1 Resistance (TIR) Domain-Containing Adapter Proteins in TLR4- versus TLR2-Mediated Signal Transduction. J. Immunol., 175: 494 - 500.
2. Derossi D. et al., 1994. The third helix of the Antennapedia homeodomain translocates through biological membranes. J. Biol. Chem., 269: 10444-50.
All products are for research use only, and not for human or veterinary use.
SPECIFICATIONS
Specifications
TRIF
Human, Mouse
RQIKIWFQNRRMKWKK-FCEEFQVPGRGELH-NH2
5-50 μM for cell culture assays
In vitro cellular assays
Each lot is functionally tested and validated using cellular assays.
CONTENTS
Contents
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Product:Pepinh-TRIF
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Cat code:tlrl-pitrif
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Quantity:2 mg
- 2 mg of lyophilized Pepinh-Control
- 2 x 1.5 ml of endotoxin-free water
Shipping & Storage
- Shipping method: Room temperature
- -20°C
- Avoid repeated freeze-thaw cycles
Storage:
Caution:
DOCUMENTS
Documents
Technical Data Sheet
Safety Data Sheet
Certificate of analysis
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