pDRIVE-hKIN
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Cat.code:
pdrive-hbkin
- Documents
ABOUT
β-Kin promoter (Ubiquitous) in pDRIVE expression plasmid
Kinesins are tubulin molecular motors whose function is to transport organelles within cells. Kinesins have been characterized as tetrameric proteins, with two heavy (α) chains and two light (β) chains.
The promoter region of the β-kinesin gene can drive the constitutive expression of a transgene in a variety of cells. The 5’UTR is able to form a stable double hairpin structure that increases the strength of the promoter by enhancing mRNA translatability.
The β-kinesin promoter encompassing the 5’UTR is 75-fold to 100-fold higher than the HSV-tk or NSE promoters [1].
Reference:
1. Chernajovsky Y. et al. 1996. Human kinesin light (β) chain gene: DNA sequence and functional characterization of its promoter and first exon. DNA Cell Biol 15(11):965-974.
All products are for internal research use only, and not for human or veterinary use.
SPECIFICATIONS
Specifications
in vitro or in vivo transfection
Ubiquitous
in vitro transfection
Plasmid construct has been confirmed by restriction analysis and full-length ORF sequencing.
CONTENTS
Contents
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Product:pDRIVE-hKIN
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Cat code:pdrive-hbkin
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Quantity:20 µg
1 ml of Zeocin® (100 mg/ml)
Shipping & Storage
- Shipping method: Room temperature
- -20°C
- Avoid repeated freeze-thaw cycles
Storage:
Caution:
DOCUMENTS
Documents
Technical Data Sheet
Plasmid Map and Sequence
Plasmid Sequence
Safety Data Sheet
Certificate of analysis
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