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pDRIVE-β-Kin

Product Unit size Cat. code Docs. Qty. Price

pDRIVE-hKIN

pDRIVE bearing human β-Kin promoter - LacZ

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20 µg

pdrive-hbkin
+-
$554

pDRIVE5SEAP-hKIN

pDRIVE bearing human β-Kin promoter - SEAP

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20 µg

pdrive5s-hbkin
+-
$554

pDRIVE5Lucia-hKIN

pDRIVE bearing human β-Kin promoter - Lucia

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20 µg

pdrive5lc-hbkin
+-
$554

β-Kin promoter (Ubiquitous) in pDRIVE expression plasmid

Kinesins are tubulin molecular motors whose function is to transport organelles within cells. Kinesins have been characterized as tetrameric proteins, with two heavy (α) chains and two light (β) chains.

The promoter region of the β-kinesin gene can drive the constitutive expression of a transgene in a variety of cells. The 5’UTR is able to form a stable double hairpin structure that increases the strength of the promoter by enhancing mRNA translatability.

The β-kinesin promoter encompassing the 5’UTR is 75-fold to 100-fold higher than the HSV-tk or NSE promoters [1].

 

Reference:

1. Chernajovsky Y. et al. 1996. Human kinesin light (β) chain gene: DNA sequence and functional characterization of its promoter and first exon. DNA Cell Biol 15(11):965-974.

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Specifications

pDRIVE bearing human β-Kin promoter - LacZ, SEAP or Lucia

Gene Promoter: Beta-Kinesin

Specificity: Ubiquitous

Backbone: pDRIVE, pDRIVE5-SEAP or pDRIVE5-Lucia

Selection: Zeocin™

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pDRIVE contents

  • 20 µg of lyophilized DNA
  • 1 ml of Zeocin™ (100 mg/ml)

room temperature Product is shipped at room temperature

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Details

pDRIVE map

pDRIVE5-SEAP map

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