pDRIVE-hUbiquitinB
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pDRIVE bearing human Ubiquitin B promoter - LacZ
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Cat.code:
pdrive-hubiquitinb
- Documents
ABOUT
Ubiquitin B promoter (Ubiquitous) in pDRIVE expression plasmid
Ubiquitin B (Ubi B) is a small highly conserved protein that is abundantly expressed in all eukaryotic cells. Ubi B is involved in the degradation of short-lived regulatory proteins as well as abnormal/mutated proteins and in the processing of major histocompatibility class I-restricted antigens [1].
A 1.1 kb fragment from the ubiquitin B gene was shown to display sustained expression of a transgene in vitro and in vivo.
Twenty days post-injection, the levels of expression were similar to those obtained with the CMV promoter and were higher 35 days post-injection [2].
References:
1. Ciechanover A. and Schwartz AL. 1998. The ubiquitin-proteasome pathway: the complexity and myriad functions of proteins death. Proc Natl Acad Sci USA 95(6):2727-30.
2. Yew NS. et al. 2001. High and sustained transgene expression in vivo from plasmid vectors containing a hybrid ubiquitin promoter. Mol Ther. 4(1):75-82.
All products are for research use only, and not for human or veterinary use.
SPECIFICATIONS
Specifications
Plasmid construct has been confirmed by restriction analysis and sequencing.
CONTENTS
Contents
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Product:pDRIVE-hUbiquitinB
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Cat code:pdrive-hubiquitinb
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Quantity:20 µg
1 ml of Zeocin™ (100 mg/ml)
Shipping & Storage
- Shipping method: Room temperature
- -20°C
Storage:
DOCUMENTS
Documents
Plasmid Map and Sequence
Safety Data Sheet
Plasmid Sequence
Technical Data Sheet
Certificate of analysis
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