Toll-like receptors (TLRs) are the best studied pattern recognition receptors (PRRs) and their importance in stimulating innate and adaptive immunity is now well established.

InvivoGen offers a mini-review of inflammasomes implication in innate and adaptive immunity. The review focuses on the central role of inflammatory cytokine release, such as IL-1 beta and IL-18, and pyroptosis, a form of programmed necrotic cell death.

The innate immune system is crucial to limit viral infections. It relies on several groups of pattern recognition receptors (PRRs) that recognize viral nucleic acids.

STING (stimulator of interferon genes), alternatively known as MPYS, TMEM173, MITA and ERIS, is a key sensor of cytosolic nucleic acids.

Mycoplasma contaminations in cell cultures is a frequent problem but can be eliminated with proper treatment. This review from InvivoGen compares existing reagents on the market: BM-Cyclin, MRA, Cyprobay, Plasmocin and Plasmocure.

Mycoplasmas frequently contaminate cell cultures. This review explains the consequences of contamination and presents InvivoGen’s reagents for mycoplasma detection, prevention and elimination.

Inflammasomes are multimeric protein complexes that are crucial for host defense to infection and endogenous danger signals.

Mycoplasmas are the smallest and simplest self-replicating organisms. Due to their minimal genome, they cannot perform metabolic functions such as production of a cell wall, or synthesis of nucleotides or amino acids.

Antibodies are immunoglobulin (Ig) molecules made up of 2 large heavy chains (~55 kDa each) and 2 small light chains (~25 kDa each).

β-Glucans have been consumed for many centuries for their healing properties. Since the discovery of their immunomodulating capabilities, about five decades ago, β-glucans have attracted a great deal of attention in the biomedical arena.