Invivogen
Menu

pINFUSE-hIgG1-Fc

pINFUSE-hIgG1-Fc1 Unit size Cat. code Docs Qty Price
20 µg
pfc1-hgin1
+-
$536.00
pINFUSE-hIgG1-Fc2 Unit size Cat. code Docs Qty Price
20 µg
pfc2-hgin1
+-
$536.00

pINFUSE-hIgG1-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the human IgG1 heavy chain and the hinge region. The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently. A short intron is present between each region (one intron between the hinge and CH2 and one intron between CH2 and CH3). The presence of introns is known to enhance the level of gene expression as splicing is known to promote rapid and efficient mRNA export.

pINFUSE-hIgG1-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted

Back to the top

Specifications

Human IgG1 displays high ADCC and CDC, and is the most suitable for therapeutic use against pathogens and cancer cells.

Both plasmids are selectable with Zeocin™.

Back to the top

Contents

• 20 μg of lyophilized DNA
• 4 pouches of E. coli Fast-Media® Zeo (2 TB and 2 Agar)

Back to the top

Citations

Customer Service
& Technical Support

CAPTCHA
In order to prevent automated spam submissions, please answer the following question:
4 + 1 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.
Shopping cart is empty