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pFUSEN-hG1Fc

pFUSEN-hG1Fc Unit size Cat. code Docs Qty Price
Fc-fusion protein expression plasmid - Human IgG1
20 µg
pfcn-hg1
+-
$536.00

pFUSEN-hG1Fc is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the human IgG1 heavy chain and the hinge region fused to the N-terminus of a protein of interest.

Human IgG1-Fc exhibits moderate to high affinity for FcγRs and complement receptors, thus triggering strong ADCC and CDC, respectively.
Currently, all Fc-fusions licensed for clinical use contain the IgG1-Fc domain.

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Specifications

Isotype: Human IgG1
Effector Activities: ADCC+++, CDC +++

Selectable with Zeocin™ in E. coli and mammalian cells.
For transient or stable transfection.

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Contents

• 20 μg of lyophilized DNA
• 4 pouches of E. coli Fast-Media® Zeo (2 TB and 2 Agar)

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Details

pFUSEN-Fc map

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