pFUSEN-hG1Fc
| Product | Unit size | Cat. code | Docs. | Qty. | Price | |
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pFUSEN-hG1Fc Fc-fusion protein expression plasmid - Human IgG1 |
Show product |
20 µg |
pfcn-hg1
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pFUSEN-hG1Fc is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the human IgG1 heavy chain and the hinge region fused to the N-terminus of a protein of interest.
Human IgG1-Fc exhibits moderate to high affinity for FcγRs and complement receptors, thus triggering strong ADCC and CDC, respectively.
Currently, all Fc-fusions licensed for clinical use contain the IgG1-Fc domain.
Specifications
Isotype: Human IgG1
Effector Activities: ADCC+++, CDC +++
Selectable with Zeocin™ in E. coli and mammalian cells.
For transient or stable transfection.
pFUSEN Contents
- 20 µg of lyophilized DNA
- 1 ml of Zeocin™ (100 mg/ml)
Product is shipped at room temperature
