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Fc-fusion protein expression plasmid - Human IgG1

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20 µg


pFUSEN-hG1Fc is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the human IgG1 heavy chain and the hinge region fused to the N-terminus of a protein of interest.

Human IgG1-Fc exhibits moderate to high affinity for FcγRs and complement receptors, thus triggering strong ADCC and CDC, respectively.
Currently, all Fc-fusions licensed for clinical use contain the IgG1-Fc domain.

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Isotype: Human IgG1
Effector Activities: ADCC+++, CDC +++

Selectable with Zeocin™ in E. coli and mammalian cells.
For transient or stable transfection.

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pFUSEN Contents

  • 20 µg of lyophilized DNA
  • 1 ml of Zeocin™ (100 mg/ml)

room temperature Product is shipped at room temperature

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