pFUSE-mIgG2a-Fc
| pFUSE-mIgG2A-Fc1 | Unit size | Cat. code | Docs | Qty | Price |
|---|---|---|---|---|---|
20 µg |
pfuse-mg2afc1 |
| pFUSE-mIgG2A-Fc2 | Unit size | Cat. code | Docs | Qty | Price |
|---|---|---|---|---|---|
20 µg |
pfuse-mg2afc2 |
pFUSE-mIgG2a-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the murine IgG2a heavy chain and the hinge region. The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently. Murine IgG2a displays high ADCC and CDC.
pFUSE-mIgG2a-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted.
Specifications
Isotype : IgG2A mouse
Effector Activities : ADCC+++, CDC +++
Protein A binding: ++++
Protein G binding: ++++
Both plasmids are selectable with Zeocin™.
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• 20 μg of lyophilized DNA
• 4 pouches of E. coli Fast-Media® Zeo (2 TB and 2 Agar)