pFUSE-mIgG1-Fc
| pFUSE-mIgG1-Fc1 | Unit size | Cat. code | Docs | Qty | Price |
|---|---|---|---|---|---|
Fc-fusion protein expression plasmid - Murine IgG1 |
20 µg |
pfuse-mg1fc1 |
| pFUSE-mIgG1-Fc2 | Unit size | Cat. code | Docs | Qty | Price |
|---|---|---|---|---|---|
Fc-fusion protein expression plasmid - Murine IgG1 |
20 µg |
pfuse-mg1fc2 |
Fc-fusion protein expression plasmid - Murine IgG1
pFUSE-mIgG1-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the murine IgG1 heavy chain and the hinge region.
The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently.
Murine IgG1 displays low ADCC and CDC.
pFUSE-mIgG1-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted.
Figures
Specifications
Isotype : IgG1 mouse
Effector Activities : ADCC-, CDC +/-
Protein A binding: +
Protein G binding: ++++
Both plasmids are selectable with Zeocin™.
Back to the topContents
- 20 μg of lyophilized DNA
- 4 pouches of E. coli Fast-Media® Zeo (2 TB and 2 Agar)
Product is shipped at room temperature.