pFUSE-hIgG4-Fc

Fc-fusion protein expression plasmid - Human IgG4

ABOUT

Fc-fusion protein expression plasmid - Human IgG4

pFUSE-hIgG4-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the human IgG4 heavy chain and the hinge region.

The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently.

Human IgG4 displays low ADCC and CDC.

pFUSE-hIgG4-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted.

All products are for research use only, and not for human or veterinary use.

SPECIFICATIONS

Specifications

Plasmid backbone
pFUSE
Antibiotic resistance
Zeocin®
Gene promoter
hEF1-HTLV prom
Purification
Ion-exchange chromatography
Reconstitution buffer
Sterile water
Quality control

Plasmid construct has been confirmed by restriction analysis and sequencing.

CONTENTS

Contents

  • Product: 
    pFUSE-hIgG4-Fc1
  • Cat code: 
    pfuse-hg40fc1
  • Quantity: 
    20 µg
Includes:

1 ml of Zeocin™ (100 mg/ml)

Shipping & Storage

  • Shipping method:  Room temperature

    • Storage:

    • -20°C
    Stability: Resuspended DNA should be stored at -20˚C and is stable up to 1 year.

    Caution:

    • Avoid repeated freeze-thaw cycles

DOCUMENTS

Documents

pFUSE-hIgG4-Fc1

Technical Data Sheet

Safety Data Sheet

Certificate of analysis

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