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pFUSE-hIgG4-Fc

pFUSE-hIgG4-Fc1 Unit size Cat. code Docs Qty Price
Fc-fusion protein expression plasmid - Human IgG4
20 µg
pfuse-hg40fc1
+-
$555.00
pFUSE-hIgG4-Fc2 Unit size Cat. code Docs Qty Price
Fc-fusion protein expression plasmid - Human IgG4 with IL2ss
20 µg
pfuse-hg40fc2
+-
$555.00

Fc-fusion protein expression plasmid - Human IgG4

pFUSE-hIgG4-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the human IgG4 heavy chain and the hinge region.

The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently.

Human IgG4 displays low ADCC and CDC.

pFUSE-hIgG4-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted.

Figures

pFUSE-hIgG4-Fc Map
pFUSE-hIgG4-Fc Map
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Specifications

Isotype : IgG4 human

Effector Activities : ADCC+/-, CDC-

Protein A binding: ++++

Protein G binding: ++++

Both plasmids are selectable with Zeocin™.

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Contents

room temperature Product is shipped at room temperature.

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Citations

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