Peptide M / Agarose

Agarose for IgA1 and IgA2 purification

ABOUT

Agarose for IgA1 and IgA2 purification

Peptide M is a 50 aa synthetic peptide derived from a streptococcal M protein containing an additional C-terminal cysteine residue.

Peptide M binds monomeric and dimeric human IgA of both subclasses (IgA1 and IgA2) with high specificity and affinity.

It also binds bovine IgA but not murine IgA. Peptide M binding occurs at a site in IgA-Fc conserved in human IgA1 and IgA2 and bovine IgA but not in mouse IgA.

Peptide M can be used for single-step affinity purification of IgA and for specific detection of antigen-bound IgA.

 

Binding capacity

  • 4 - 6 mg human IgA per ml of gel

 

Reference:

1. Sandin C. et al., 2002. Isolation and detection of human IgA using a streptococcal IgA binding peptide. J Immunol. 169(3):1357-64.

All InvivoGen products are for internal research use only, and not for human or veterinary use.

SPECIFICATIONS

Specifications

Applications

IgA1 and IgA2 purification

Source
Synthetic
Formulation buffer

50% v/v gel slurry in PBS 20% v/v ethanol

Appearance (form)
Liquid
Appearance (color)
Colorless

CONTENTS

Contents

  • Product: 
    Peptide M / Agarose
  • Cat code: 
    gel-pdm-2
  • Quantity: 
    2 ml
Notes:

Provided as a 50% v/v gel slurry in PBS 20% v/v ethanol (total volume 4 ml)

DO NOT FREEZE

Shipping & Storage

  • Shipping method:  Room temperature
  • Storage:

    • 4°C
    Stability: 4°C for up to 1 year

    Caution:

    • Do not freeze

DOCUMENTS

Documents

Peptide M / Agarose

Technical Data Sheet

Safety Data Sheet

Certificate of analysis

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CUSTOMER SERVICE & TECHNICAL SUPPORT

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