pDRIVE-Mb
| Product | Unit size | Cat. code | Docs. | Qty. | Price | |
|---|---|---|---|---|---|---|
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pDRIVE-hMb pDRIVE bearing human Mb promoter - LacZ |
Show product |
20 µg |
pdrive-hmb
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pDRIVE5SEAP-hMb pDRIVE bearing human Mb promoter - SEAP |
Show product |
20 µg |
pdrive5s-hmb
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pDRIVE5Lucia-hMb pDRIVE bearing human Mb promoter - Lucia |
Show product |
20 µg |
pdrive5lc-hmb
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pDRIVE-mMb pDRIVE bearing mouse Mb promoter - LacZ |
Show product |
20 µg |
pdrive-mmb
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pDRIVE5SEAP-mMb pDRIVE bearing mouse Mb promoter - SEAP |
Show product |
20 µg |
pdrive5s-mmb
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pDRIVE5Lucia-mMb pDRIVE bearing mouse Mb promoter - Lucia |
Show product |
20 µg |
pdrive5lc-mmb
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Mb promoter (Muscle) in pDRIVE expression plasmid
Myoglobin is a cytoplasmic hemoprotein that binds molecular oxygen to facilitate its diffusion from the vascular system to the muscle mitochondria.
Myoglobin is found only in muscle, predominantly in cardiac and skeletal myocytes.
he myoglobin promoter can drive the expression of a transgene in multinucleated myotubes but not in mononucleated and undifferentiated cells [1].
This capacity is conferred by a small segment of the 5’ flanking region extending from nucleotides -357 to +55 relative to the transcriptional start site [2].
References:
1. Devlin BH. et al. 1989. Identification of a muscle-specific enhancer within the 5’-flanking region of the human myoglobin gene. J Biol Chem 264(23):13896-13901.
2. Yan Z. et al. 2001. Regulatory elements governing transcription in specialized myofiber subtypes. J Biol Chem 276(20):17361-17366.
Specifications
pDRIVE bearing human Mb promoter - LacZ, SEAP or Lucia
Gene Promoter: Myoglobin
Specificity: Muscle
Backbone: pDRIVE, pDRIVE5-SEAP or pDRIVE5-Lucia
Selection: Zeocin™
pDRIVE bearing mouse Mb promoter - LacZ, SEAP or Lucia
Gene: Myoglobin
Specificity: Muscle
Backbone: pDRIVE, pDRIVE5-SEAP or pDRIVE5-Lucia
Selection: Zeocin™
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pDRIVE contents
- 20 µg of lyophilized DNA
- 1 ml of Zeocin™ (100 mg/ml)
Product is shipped at room temperature
