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Anti-hCD20-hIgE

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Anti-hCD20-hIgE

Human CD20 (rituximab) antibody - Human IgE

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hcd20-mab8

This antibody has been removed from our catalog. However, you may contact us if you wish to order minimal quantities.

Monoclonal human IgE antibody against human CD20

Anti-hCD20-hIgE features the constant region of the human IgE isotype and the variable region of rituximab.

Rituximab is a mouse/human chimeric monoclonal antibody that targets the CD20 antigen found on the surface of malignant and normal B lymphocytes.

Binding of rituximab to CD20 results in cell destruction through different mechanisms including direct signaling of apoptosis, complement activation and cell-mediated cytotoxicity.

Rituximab has been approved by the FDA for the treatment of various lymphoid malignancies, including B-cell non-Hodgkin's lymphoma and B-cell chronic lymphocytic leukaemia.

Anti-hCD20-hIgE was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with protein L.

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Specifications

Clonality: Monoclonal antibody

Specificity: Targets cells expressing human CD20

Isotype: Human IgE, kappa

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Contents

  • 100 µg purified anti-hCD20-hIgE antibody, provided azide-free and lyophilized.

room temperature Product is shipped at room temperature.

store Store lyophilized antibody at -20°C.

stability Lyophilized product is stable for 1 year.

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