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Anti-hCD20-hIgE

Anti-hCD20-hIgE Unit size Cat. code Docs Price
Human CD20 (rituximab) antibody - Human IgE
Custom size
hcd20-mab8

January 20th, 2020.
This antibody has been removed from our catalog. However, you may contact us if you wish to order minimal quantities.

Monoclonal human IgE antibody against human CD20

Anti-hCD20-hIgE features the constant region of the human IgE isotype and the variable region of rituximab.

Rituximab is a mouse/human chimeric monoclonal antibody that targets the CD20 antigen found on the surface of malignant and normal B lymphocytes.

Binding of rituximab to CD20 results in cell destruction through different mechanisms including direct signaling of apoptosis, complement activation and cell-mediated cytotoxicity.

Rituximab has been approved by the FDA for the treatment of various lymphoid malignancies, including B-cell non-Hodgkin's lymphoma and B-cell chronic lymphocytic leukaemia.

Anti-hCD20-hIgE was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with protein L.

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Specifications

Clonality: Monoclonal antibody

Specificity: Targets cells expressing human CD20

Isotype: Human IgE, kappa

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Contents

  • 100 µg purified anti-hCD20-hIgE antibody, provided azide-free and lyophilized.

room temperature Product is shipped at room temperature.

store Store lyophilized antibody at -20°C.

stability Lyophilized product is stable for 1 year.

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Citations

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