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Anti-β-Gal-hIgG1

Anti-β-Gal-hIgG1 Unit size Cat. code Docs Qty Price
Isotype control - Human IgG1
200 µg
bgal-mab1
+-
$301.00

Monoclonal human IgG1 antibody against E. coli β-galactosidase

Anti-β-Gal-hIgG1 features the constant region of the human IgG1 isotype and the variable region of Mouse IgG2a Control. Mouse IgG2a Control is a mouse IgG2a monoclonal antibody that targets E. coli β-galactosidase (β-Gal). This antibody was generated by DNA immunization with a plasmid expressing the β-Gal gene in Swiss mice. It can be used as an isotype control for human IgG1 antibodies.
Human IgG1 is the most abundant immunoglobin present in serum and binds with high affinity to the Fc receptor on phagocytic cells. The human IgG1 isotype displays high antibody-dependent cell-mediated cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC).
Anti-β-Gal-hIgG1 was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity  chromatography.

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Specifications

Clonality: Monoclonal antibody
Specificity: Targets cells expressing E. coli β-galactosidase (β-Gal)
Isotype:
Human IgG1
Application: Negative control for human IgG1 antibodies

Quality control:
- The absence of binding of Anti-β-Gal-hIgG1 to human cell lines has been controlled using flow cytometry.
- The absence of endotoxins and other bacterial contaminants has been confirmed using HEK-Blue™ TLR4 and HEK-Blue™ TLR2 cells.

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Contents

200 µg purified anti-β-Gal-IgG1 antibody, provided azide-free and lyophilized

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